Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.

Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.

The objective of our study was to identify genetic factors that regulate bone mineral density (BMD) in mice using well defined recombinant inbred strains. For this purpose we chose the BXD recombinant inbred (RI) strains derived from progeny of the C57BL/6J (B6) and DBA/2J (D2) progenitor strains. W...

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Main Authors: Lishi Wang, Wenli Lu, Lei Zhang, Yue Huang, Rachel Scheib, Xiaoyun Liu, Linda Myers, Lu Lu, Charles R Farber, Gaifen Liu, Cong-Yi Wang, Hongwen Deng, Robert W Williams, Yongjun Wang, Weikuan Gu, Yan Jiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0084485&type=printable
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