TRANSCRIPTION FACTOR BRN-3α AND PROSTATE CANCER, RELATION WITH HORMONE RECEPTORS AND AKT/M-TOR SIGNALING PATHWAY ACTIVATION

TRANSCRIPTION FACTOR BRN-3α AND PROSTATE CANCER, RELATION WITH HORMONE RECEPTORS AND AKT/M-TOR SIGNALING PATHWAY ACTIVATION

Introduction. The transcription factor Brn-3α (product of the POU4F1) plays a significant role in carcinogenesis. The purpose of the study was to investigate Brn-3α, AR, ERα expressions in tissues of benign prostatic hyperplasia and prostate cancer as well as to determine their association with AKT/...

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Bibliographic Details
Main Authors: L. V. Spirina, A. K. Gorbunov, I. V. Kondakova, E. M. Slonimskaya, E. A. Usynin
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2018-03-01
Series:Сибирский онкологический журнал
Subjects:
brn-3α
transcription factor
prostate cancer
ar
er
akt/m-tor signaling pathway
Online Access:https://www.siboncoj.ru/jour/article/view/667
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