重组人内皮抑素对胃肠间质瘤血管形成及生长的抑制作用
【目的】 研究重组人内皮抑素(recombinant human endostatin,rhES)能否抑制胃肠间质瘤(gastrointestinal stromal tumor,GIST)裸鼠移植肿瘤血管生成及生长,探讨抑制血管形成作为GIST治疗方法的可行性65377;【方法】 随机将20只荷瘤裸鼠分为实验组与对照组65377;对照组瘤周注射生理盐水,实验组瘤周注射rhES,连用10 d65377;自用药开始,每5 d测量肿瘤体积,直至用药结束后5 d65377;计算抑瘤率和肿瘤缩小率65377;比较实验组与对照组肿瘤体积65380;微血管密度(microvascular density,...
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| Format: | Article |
|---|---|
| Language: | zho |
| Published: |
Editorial Office of Journal of Sun Yat-sen University
2010-01-01
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| Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
| Subjects: | |
| Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43576709/ |
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