Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study.
Limited clinical data exists on the peri-implant microbiome in edentulous patients with implant-retained overdentures (IRO). This study aimed to examine the peri-implant microbiome and its correlation with pre-treatment periodontal diagnosis. A total of twenty-five patients with 50 implants were inc...
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| Format: | Article |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0325711 |
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| author | Xiaoxi Cui Acela A Martinez Luna Alex Gillone Qiang Wu Mahmoud Serag Ramiro Mendonca Murata |
| author_facet | Xiaoxi Cui Acela A Martinez Luna Alex Gillone Qiang Wu Mahmoud Serag Ramiro Mendonca Murata |
| author_sort | Xiaoxi Cui |
| collection | DOAJ |
| description | Limited clinical data exists on the peri-implant microbiome in edentulous patients with implant-retained overdentures (IRO). This study aimed to examine the peri-implant microbiome and its correlation with pre-treatment periodontal diagnosis. A total of twenty-five patients with 50 implants were included, with demographic information and pre-treatment periodontal diagnosis collected. Clinical measurements and subgingival plaque samples were obtained from each implant, followed by 16S rRNA gene-targeted sequencing. Peri-implant parameters and microbiome were analyzed in relation to gender, remaining teeth prior to treatment, IRO function time, implant system, bone graft at implant placement, and peri-implant diagnosis. The mean age of patients was 71 years, with pre-extraction diagnoses including clinical healthy gingiva on a reduced periodontium (4 patients), localized periodontitis (4 patients), generalized periodontitis (7 patients), and generalized Stage IV Grade C periodontitis (10 patients). Nineteen implants were diagnosed with peri-implant mucositis, while 31 were healthy. The predominant genera detected were Streptococcus, Rothia, Veillonella, Actinomyces, and Schaalia. No significant correlation was found between pre-treatment periodontal diagnosis and peri-implant diagnosis. The findings suggest that while pre-extraction periodontal diagnosis might influence the peri-implant subgingival microbiome in IRO patients, it may not correlate with the clinical peri-implant diagnosis. |
| format | Article |
| id | doaj-art-33409672a9d64ac882e93362483dbd0f |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-33409672a9d64ac882e93362483dbd0f2025-08-20T02:39:41ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01207e032571110.1371/journal.pone.0325711Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study.Xiaoxi CuiAcela A Martinez LunaAlex GilloneQiang WuMahmoud SeragRamiro Mendonca MurataLimited clinical data exists on the peri-implant microbiome in edentulous patients with implant-retained overdentures (IRO). This study aimed to examine the peri-implant microbiome and its correlation with pre-treatment periodontal diagnosis. A total of twenty-five patients with 50 implants were included, with demographic information and pre-treatment periodontal diagnosis collected. Clinical measurements and subgingival plaque samples were obtained from each implant, followed by 16S rRNA gene-targeted sequencing. Peri-implant parameters and microbiome were analyzed in relation to gender, remaining teeth prior to treatment, IRO function time, implant system, bone graft at implant placement, and peri-implant diagnosis. The mean age of patients was 71 years, with pre-extraction diagnoses including clinical healthy gingiva on a reduced periodontium (4 patients), localized periodontitis (4 patients), generalized periodontitis (7 patients), and generalized Stage IV Grade C periodontitis (10 patients). Nineteen implants were diagnosed with peri-implant mucositis, while 31 were healthy. The predominant genera detected were Streptococcus, Rothia, Veillonella, Actinomyces, and Schaalia. No significant correlation was found between pre-treatment periodontal diagnosis and peri-implant diagnosis. The findings suggest that while pre-extraction periodontal diagnosis might influence the peri-implant subgingival microbiome in IRO patients, it may not correlate with the clinical peri-implant diagnosis.https://doi.org/10.1371/journal.pone.0325711 |
| spellingShingle | Xiaoxi Cui Acela A Martinez Luna Alex Gillone Qiang Wu Mahmoud Serag Ramiro Mendonca Murata Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. PLoS ONE |
| title | Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. |
| title_full | Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. |
| title_fullStr | Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. |
| title_full_unstemmed | Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. |
| title_short | Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. |
| title_sort | correlation between pre extraction periodontal diagnosis and peri implant microbiome for patients treated with implant retained overdenture a retrospective cohort pilot study |
| url | https://doi.org/10.1371/journal.pone.0325711 |
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