Death-ision: the link between cellular resilience and cancer resistance to treatments

Abstract One of the key challenges in defeating advanced tumors is the ability of cancer cells to evade the selective pressure imposed by chemotherapy, targeted therapies, immunotherapy and cellular therapies. Both genetic and epigenetic alterations contribute to the development of resistance, allow...

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Bibliographic Details
Main Authors: Gustavo Baldassarre, Ivana L. de la Serna, François M. Vallette
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Molecular Cancer
Online Access:https://doi.org/10.1186/s12943-025-02339-1
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