Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry

The 2021 FSIS Appendix B guidelines restrict cooling of meat and poultry products to limit the growth of Clostridium perfringens to no greater than 1-log. This study compared the effect of pH and salt on the growth of 3 sporeforming pathogens, Clostridium perfringens, Bacillus cereus, and Clostridiu...

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Main Authors: Brandon J. Wanless, Jeff Sindelar, Kathleen Ann Glass, Max C Golden
Format: Article
Language:English
Published: Iowa State University Digital Press 2024-09-01
Series:Meat and Muscle Biology
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Online Access:https://www.iastatedigitalpress.com/mmb/article/id/17650/
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author Brandon J. Wanless
Jeff Sindelar
Kathleen Ann Glass
Max C Golden
author_facet Brandon J. Wanless
Jeff Sindelar
Kathleen Ann Glass
Max C Golden
author_sort Brandon J. Wanless
collection DOAJ
description The 2021 FSIS Appendix B guidelines restrict cooling of meat and poultry products to limit the growth of Clostridium perfringens to no greater than 1-log. This study compared the effect of pH and salt on the growth of 3 sporeforming pathogens, Clostridium perfringens, Bacillus cereus, and Clostridium botulinum during extended cooling in an uncured poultry product. Nine turkey treatments (75% moisture) were formulated using a full factorial design (pH 5.8, 6.2, 6.6; salt 1.2%, 1.5%, 1.8%). Treatments were inoculated with 3-log spores/g of C. perfringens, B. cereus, or C. botulinum and vacuum-packaged (25 g/package). Samples were cooked to 73°C, then cooled from 48.9 °C to 26.7 °C (phase 1) in 1, 1.5, 2, 2.5, or 3 h, from 26.7 °C to 12.8°C (phase 2) and from 12.8°C to 4.4°C (phase 3) in 5 h each. Samples were assayed by enumerating on selective agars at 0-time (post cook before incubation) and at internal temperatures 48.9, 26.7, and 4.4 C. C. botulinum grew < 1-log, and no botulinum toxin was detected regardless of cooling rate or formulation tested. B. cereus was inhibited in all formulations through the 12.5 h total cool (2.5-h phase 1 cooling), but > 1-log increase was observed in pH 6.6 formulations for 13-h total cool. Less than a 1-log C. perfringens growth was detected for all treatments when phase 1 cooling was limited to 1 h, with 1.5-h phase 1 cool for pH < 6.2 with > 1.2% salt, pH 6.6 with > 1.5% salt, and 2-h phase 1 cool for pH < 5.8 and 1.8% salt. All formulations supported a 1- to 3-log increase of C. perfringens when phase 1 cool was 3 h. This study confirms cooling conditions that inhibit C. perfringens will likewise inhibit C. botulinum and B. cereus for the duration of the cooling, and phase 1 cooling can be extended up to 2.5 h depending on salt/pH combinations.
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spelling doaj-art-333494d3fff943b09c2201b18507536d2025-08-20T02:45:11ZengIowa State University Digital PressMeat and Muscle Biology2575-985X2024-09-018110.22175/mmb.17650Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured PoultryBrandon J. Wanless0Jeff SindelarKathleen Ann Glass1https://orcid.org/0000-0002-7996-1116Max C Golden2Food Research Institute, University of Wisconsin-MadisonFood Research Institute, University of Wisconsin-MadisonFood Research Institute, University of Wisconsin-MadisonThe 2021 FSIS Appendix B guidelines restrict cooling of meat and poultry products to limit the growth of Clostridium perfringens to no greater than 1-log. This study compared the effect of pH and salt on the growth of 3 sporeforming pathogens, Clostridium perfringens, Bacillus cereus, and Clostridium botulinum during extended cooling in an uncured poultry product. Nine turkey treatments (75% moisture) were formulated using a full factorial design (pH 5.8, 6.2, 6.6; salt 1.2%, 1.5%, 1.8%). Treatments were inoculated with 3-log spores/g of C. perfringens, B. cereus, or C. botulinum and vacuum-packaged (25 g/package). Samples were cooked to 73°C, then cooled from 48.9 °C to 26.7 °C (phase 1) in 1, 1.5, 2, 2.5, or 3 h, from 26.7 °C to 12.8°C (phase 2) and from 12.8°C to 4.4°C (phase 3) in 5 h each. Samples were assayed by enumerating on selective agars at 0-time (post cook before incubation) and at internal temperatures 48.9, 26.7, and 4.4 C. C. botulinum grew < 1-log, and no botulinum toxin was detected regardless of cooling rate or formulation tested. B. cereus was inhibited in all formulations through the 12.5 h total cool (2.5-h phase 1 cooling), but > 1-log increase was observed in pH 6.6 formulations for 13-h total cool. Less than a 1-log C. perfringens growth was detected for all treatments when phase 1 cooling was limited to 1 h, with 1.5-h phase 1 cool for pH < 6.2 with > 1.2% salt, pH 6.6 with > 1.5% salt, and 2-h phase 1 cool for pH < 5.8 and 1.8% salt. All formulations supported a 1- to 3-log increase of C. perfringens when phase 1 cool was 3 h. This study confirms cooling conditions that inhibit C. perfringens will likewise inhibit C. botulinum and B. cereus for the duration of the cooling, and phase 1 cooling can be extended up to 2.5 h depending on salt/pH combinations.https://www.iastatedigitalpress.com/mmb/article/id/17650/Clostridium perfringensClostridium botulinumBacillus cereuscoolingUSDA-FSIS Appendix Bmodel validation
spellingShingle Brandon J. Wanless
Jeff Sindelar
Kathleen Ann Glass
Max C Golden
Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry
Meat and Muscle Biology
Clostridium perfringens
Clostridium botulinum
Bacillus cereus
cooling
USDA-FSIS Appendix B
model validation
title Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry
title_full Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry
title_fullStr Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry
title_full_unstemmed Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry
title_short Comparison of Growth Inhibition of Clostridium perfringens, Clostridium botulinum, and Bacillus cereus During Extended Cooling of Uncured Poultry
title_sort comparison of growth inhibition of clostridium perfringens clostridium botulinum and bacillus cereus during extended cooling of uncured poultry
topic Clostridium perfringens
Clostridium botulinum
Bacillus cereus
cooling
USDA-FSIS Appendix B
model validation
url https://www.iastatedigitalpress.com/mmb/article/id/17650/
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