A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia
Introduction. Ibrutinib is commonly used for the treatment of patients with CLL in either first-line or relapsed/refractory settings. Case Presentation. We present the case of a 74-year-old Caucasian man with CLL who presented with penile gangrene upon initiation of ibrutinib treatment. Our case is...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/6980198 |
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| author | William Paul Skelton IV Neeka N. Akhavan Zachary A. Taylor Thu-Cuc Nguyen Hassan Hassan Tabitha N. Townsend Prajwol Pathak Gaurav Trikha Nam H. Dang Long H. Dang Azka Ali |
| author_facet | William Paul Skelton IV Neeka N. Akhavan Zachary A. Taylor Thu-Cuc Nguyen Hassan Hassan Tabitha N. Townsend Prajwol Pathak Gaurav Trikha Nam H. Dang Long H. Dang Azka Ali |
| author_sort | William Paul Skelton IV |
| collection | DOAJ |
| description | Introduction. Ibrutinib is commonly used for the treatment of patients with CLL in either first-line or relapsed/refractory settings. Case Presentation. We present the case of a 74-year-old Caucasian man with CLL who presented with penile gangrene upon initiation of ibrutinib treatment. Our case is the first showing the complication of penile gangrene associated with ibrutinib use. The gangrene was self-limited upon discontinuing ibrutinib. Conclusion. Our finding describes a very rare yet important adverse event associated with ibrutinib use. |
| format | Article |
| id | doaj-art-3332624ee9db42b6a4dd88b5cf2b2bb6 |
| institution | OA Journals |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-3332624ee9db42b6a4dd88b5cf2b2bb62025-08-20T02:24:21ZengWileyCase Reports in Oncological Medicine2090-67062090-67142016-01-01201610.1155/2016/69801986980198A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic LeukemiaWilliam Paul Skelton IV0Neeka N. Akhavan1Zachary A. Taylor2Thu-Cuc Nguyen3Hassan Hassan4Tabitha N. Townsend5Prajwol Pathak6Gaurav Trikha7Nam H. Dang8Long H. Dang9Azka Ali10Department of Internal Medicine, University of Florida, Gainesville, FL, USADepartment of Internal Medicine, University of Florida, Gainesville, FL, USADepartment of Internal Medicine, University of Florida, Gainesville, FL, USADepartment of Internal Medicine, University of Central Florida, Orlando, FL, USACancer Specialists of North Florida, Saint Augustine, FL, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida, Gainesville, FL, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida, Gainesville, FL, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida, Gainesville, FL, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida, Gainesville, FL, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida, Gainesville, FL, USADepartment of Internal Medicine, University of Florida, Gainesville, FL, USAIntroduction. Ibrutinib is commonly used for the treatment of patients with CLL in either first-line or relapsed/refractory settings. Case Presentation. We present the case of a 74-year-old Caucasian man with CLL who presented with penile gangrene upon initiation of ibrutinib treatment. Our case is the first showing the complication of penile gangrene associated with ibrutinib use. The gangrene was self-limited upon discontinuing ibrutinib. Conclusion. Our finding describes a very rare yet important adverse event associated with ibrutinib use.http://dx.doi.org/10.1155/2016/6980198 |
| spellingShingle | William Paul Skelton IV Neeka N. Akhavan Zachary A. Taylor Thu-Cuc Nguyen Hassan Hassan Tabitha N. Townsend Prajwol Pathak Gaurav Trikha Nam H. Dang Long H. Dang Azka Ali A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia Case Reports in Oncological Medicine |
| title | A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia |
| title_full | A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia |
| title_fullStr | A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia |
| title_full_unstemmed | A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia |
| title_short | A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia |
| title_sort | novel case of penile gangrene in a patient treated with ibrutinib for chronic lymphocytic leukemia |
| url | http://dx.doi.org/10.1155/2016/6980198 |
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