Synergistic action between peptide-neomycin conjugates and polymyxin B against multidrug-resistant gram-negative pathogens

Globally, it is predicted that by 2050, 10 million people will die annually because of infections with drug-resistant bacteria. Since antibacterial agents with novel mechanisms of action have not been developed in the past 30 years, there has been a surge of interest in combination therapies using e...

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Bibliographic Details
Main Authors: Sandra Story, Liuwei Jiang, Alain S. Leutou, Dev P. Arya
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1605813/full
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