A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer

The case of successful combined modality treatment in patient with stage IIIB T4bN1M0 breast cancer is reported. The first step included 2 courses of neoadjuvant polychemotherapy in CAF regimen with decrease of tumor size. The second step was irradiation (total dose of 45 Gy) of breast and areas of...

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Main Authors: E. К. Saribekyan, D. D. Pak
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2013-06-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/14
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author E. К. Saribekyan
D. D. Pak
author_facet E. К. Saribekyan
D. D. Pak
author_sort E. К. Saribekyan
collection DOAJ
description The case of successful combined modality treatment in patient with stage IIIB T4bN1M0 breast cancer is reported. The first step included 2 courses of neoadjuvant polychemotherapy in CAF regimen with decrease of tumor size. The second step was irradiation (total dose of 45 Gy) of breast and areas of regional metastasis. The third step was radical mastectomy by Madden with polypositional intraoperative photodynamic therapy with photosens (the output laser power 1500 mW, light dose 30 J/cm2, total time of irradiation – 25.6 min). The histological study of surgical specimen showed infiltrative ductal carcinoma with metastases in 3 nodes without fat invasion. In the post-operative period the patient had 3 courses of adjuvant chemotherapy in CAF regimen. Currently the duration of recurrence-free survival after treatment is 4 years.
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issn 2413-9432
language Russian
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publisher Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
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spelling doaj-art-331faa9db39349b4ae5baf547c838ce42025-08-20T03:35:32ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322013-06-0122232514A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancerE. К. Saribekyan0D. D. Pak1P.A. Herzen Moscow Cancer Research Institute, MoscowP.A. Herzen Moscow Cancer Research Institute, MoscowThe case of successful combined modality treatment in patient with stage IIIB T4bN1M0 breast cancer is reported. The first step included 2 courses of neoadjuvant polychemotherapy in CAF regimen with decrease of tumor size. The second step was irradiation (total dose of 45 Gy) of breast and areas of regional metastasis. The third step was radical mastectomy by Madden with polypositional intraoperative photodynamic therapy with photosens (the output laser power 1500 mW, light dose 30 J/cm2, total time of irradiation – 25.6 min). The histological study of surgical specimen showed infiltrative ductal carcinoma with metastases in 3 nodes without fat invasion. In the post-operative period the patient had 3 courses of adjuvant chemotherapy in CAF regimen. Currently the duration of recurrence-free survival after treatment is 4 years.https://www.pdt-journal.com/jour/article/view/14breast cancercombined modality treatmentintraoperative photodynamic therapyphotosens
spellingShingle E. К. Saribekyan
D. D. Pak
A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer
Biomedical Photonics
breast cancer
combined modality treatment
intraoperative photodynamic therapy
photosens
title A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer
title_full A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer
title_fullStr A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer
title_full_unstemmed A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer
title_short A case report of successful intraoperative photo- dynamic therapy as the step of combined modality treatment in patient with stage IIIb breast cancer
title_sort case report of successful intraoperative photo dynamic therapy as the step of combined modality treatment in patient with stage iiib breast cancer
topic breast cancer
combined modality treatment
intraoperative photodynamic therapy
photosens
url https://www.pdt-journal.com/jour/article/view/14
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AT eksaribekyan casereportofsuccessfulintraoperativephotodynamictherapyasthestepofcombinedmodalitytreatmentinpatientwithstageiiibbreastcancer
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