D-optimal design model and biosynthetic pathway for gentamicin production by Micromonospora purpureochromogenes NRRL B-16094

D-optimal design model and biosynthetic pathway for gentamicin production by Micromonospora purpureochromogenes NRRL B-16094

Abstract Background Micromonospora purpureochromogenes NRRL B-16094, a natural producer of gentamicin (GEN), a 5,6-diglycosylated 2-dexoystreptamine-aminoglycoside antibiotic (2DOS-AGA) broad-spectrum bactericidal activity. In literature, limited studies are concerned with the biosynthetic route and...

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Bibliographic Details
Main Authors: Muath Suliman, Amr S. Bishr, Sally T. K. Tohamy, Mohammad Y. Alshahrani, Khaled M. Aboshanab
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Microbiology
Subjects:
Gentamicin
Kanamycin
Fortimicin
D-optimal design Micromonospora purpureochromogenes NRRL B-16094
Online Access:https://doi.org/10.1186/s12866-025-04001-8
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