Pulse transit time as an index of vascular reactivity

Pulse transit time (PTT) is a non-invasive method for measuring arterial compliance and stiffness, which are excellent predictors of cardiovascular disease. This study aims to determine whether PTT can be used to precisely monitor vascular reactivity in response to changes in hand posture and wheth...

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Main Authors: Sheamaa Ahmed Abdullah, Samar Imran Essa, Bassam Talib Al-Gailani
Format: Article
Language:English
Published: Pakistan Medical Association 2024-09-01
Series:Journal of the Pakistan Medical Association
Online Access:https://jpma.org.pk/index.php/public_html/article/view/21916
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author Sheamaa Ahmed Abdullah
Samar Imran Essa
Bassam Talib Al-Gailani
author_facet Sheamaa Ahmed Abdullah
Samar Imran Essa
Bassam Talib Al-Gailani
author_sort Sheamaa Ahmed Abdullah
collection DOAJ
description Pulse transit time (PTT) is a non-invasive method for measuring arterial compliance and stiffness, which are excellent predictors of cardiovascular disease. This study aims to determine whether PTT can be used to precisely monitor vascular reactivity in response to changes in hand posture and whether the digital pulse wave index of time-to-maximum slope (TMS) is a suitable alternative to PTT. Fifteen healthy, 22-year-old males participated in the study. The PTT was monitored from electrocardiogram (ECG) to digital pulse wave (DPW), and the morphological variable TMS of the DPW wave was estimated in beat-tobeat intervals for the individuals while their arms were raised and dropped. The results demonstrated that the PTT increased significantly with elevating the hand, and the correlation probability of the second polynomial fitness equation neared infinite. In addition, the PTT significantly correlated (P<0.007) with the TMS of the DPW throughout the hand motions. The data indicate that PTT can represent local vascular responses during changes in hand position. In this study, we developed a new DPW index and suggest a TMS index as a viable substitute for PTT. Keywords: Cardiovascular, Electrocardiography, Pulse
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institution Kabale University
issn 0030-9982
language English
publishDate 2024-09-01
publisher Pakistan Medical Association
record_format Article
series Journal of the Pakistan Medical Association
spelling doaj-art-3308693a48944ea7b69cc6530c8acc502025-08-20T03:40:06ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-09-017410 (Supple-08)10.47391/JPMA-BAGH-16-81Pulse transit time as an index of vascular reactivitySheamaa Ahmed Abdullah0Samar Imran Essa1Bassam Talib Al-Gailani2Department of Family and Community Medicine, Mustansiriyah University, Baghdad, Iraq.Department of Physics College of Science, University of Baghdad, Iraq.Department of Physiology and Medical Physics, Mustansiriyah University. Baghdad, Iraq. Pulse transit time (PTT) is a non-invasive method for measuring arterial compliance and stiffness, which are excellent predictors of cardiovascular disease. This study aims to determine whether PTT can be used to precisely monitor vascular reactivity in response to changes in hand posture and whether the digital pulse wave index of time-to-maximum slope (TMS) is a suitable alternative to PTT. Fifteen healthy, 22-year-old males participated in the study. The PTT was monitored from electrocardiogram (ECG) to digital pulse wave (DPW), and the morphological variable TMS of the DPW wave was estimated in beat-tobeat intervals for the individuals while their arms were raised and dropped. The results demonstrated that the PTT increased significantly with elevating the hand, and the correlation probability of the second polynomial fitness equation neared infinite. In addition, the PTT significantly correlated (P<0.007) with the TMS of the DPW throughout the hand motions. The data indicate that PTT can represent local vascular responses during changes in hand position. In this study, we developed a new DPW index and suggest a TMS index as a viable substitute for PTT. Keywords: Cardiovascular, Electrocardiography, Pulse https://jpma.org.pk/index.php/public_html/article/view/21916
spellingShingle Sheamaa Ahmed Abdullah
Samar Imran Essa
Bassam Talib Al-Gailani
Pulse transit time as an index of vascular reactivity
Journal of the Pakistan Medical Association
title Pulse transit time as an index of vascular reactivity
title_full Pulse transit time as an index of vascular reactivity
title_fullStr Pulse transit time as an index of vascular reactivity
title_full_unstemmed Pulse transit time as an index of vascular reactivity
title_short Pulse transit time as an index of vascular reactivity
title_sort pulse transit time as an index of vascular reactivity
url https://jpma.org.pk/index.php/public_html/article/view/21916
work_keys_str_mv AT sheamaaahmedabdullah pulsetransittimeasanindexofvascularreactivity
AT samarimranessa pulsetransittimeasanindexofvascularreactivity
AT bassamtalibalgailani pulsetransittimeasanindexofvascularreactivity