Ivermectin inhibits the growth of ESCC by activating the ATF4-mediated endoplasmic reticulum stress-autophagy pathway

Ivermectin inhibits the growth of ESCC by activating the ATF4-mediated endoplasmic reticulum stress-autophagy pathway

Esophageal squamous cell carcinoma (ESCC) is one of the most common forms of malignancy worldwide. However, there is currently a lack of effective chemotherapeutic drugs for ESCC. Ivermectin is a broad-spectrum antiparasitic drug with notable antitumor activity. However, the cellular and molecular m...

Full description

Saved in:
Bibliographic Details
Main Authors: Liu Huiyang, Chai Zhirong, Gao Ya, Wang Yanming, Lu Mengmeng
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-11-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
ivermectin
ESCC
ER stress
ATF4
autophagy
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024210
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items