Therapeutic potential of miR-204-5p in intervertebral disc degeneration: targeting the SSRP1/NF-κB pathway to inhibit apoptosis

Abstract Background Intervertebral disc degeneration (IVDD) is a leading cause of lower back pain, imposing significant healthcare burdens globally. However, the molecular mechanisms underlying IVDD remain elusive, limiting effective therapeutic approaches. This study investigated the protective rol...

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Bibliographic Details
Main Authors: Chenhao Zhao, Qiuwei Li, Cailiang Shen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Orthopaedic Surgery and Research
Online Access:https://doi.org/10.1186/s13018-025-05999-3
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