Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease
Nocardia is an aerobic, Gram-positive, partially acid-fast bacterium that often manifests as pulmonary infection since the primary route of entry is via the respiratory tract. As an opportunistic organism, Nocardia primarily affects immunocompromised individuals. Infection with Nocardia is uncommon....
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2020/1532875 |
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| _version_ | 1849387153715363840 |
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| author | Steven A. Svoboda Joshua D. Eikenberg |
| author_facet | Steven A. Svoboda Joshua D. Eikenberg |
| author_sort | Steven A. Svoboda |
| collection | DOAJ |
| description | Nocardia is an aerobic, Gram-positive, partially acid-fast bacterium that often manifests as pulmonary infection since the primary route of entry is via the respiratory tract. As an opportunistic organism, Nocardia primarily affects immunocompromised individuals. Infection with Nocardia is uncommon. Primary cutaneous nocardiosis which is caused by percutaneous inoculation is even more rare. Here, we report a case of primary cutaneous nocardiosis in an adolescent with Crohn disease receiving treatment with adalimumab and azathioprine. Early identification and treatment are important to prevent disease progression and to avoid severe complications. Diagnosis is made principally by culture. Given that culture results may take up to two weeks to return, primary cutaneous nocardiosis should be maintained in the differential for any superficial cutaneous infection that arises in individuals undergoing treatment with immunosuppressive agents. |
| format | Article |
| id | doaj-art-32fbe7f3d8cf41abb7459051e82118b6 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-32fbe7f3d8cf41abb7459051e82118b62025-08-20T03:55:17ZengWileyCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/15328751532875Primary Cutaneous Nocardiosis in an Adolescent with Crohn DiseaseSteven A. Svoboda0Joshua D. Eikenberg1Virginia Tech Carilion School of Medicine, Roanoke, VA, USASection of Dermatology, Virginia Tech Carilion School of Medicine, Roanoke, VA, USANocardia is an aerobic, Gram-positive, partially acid-fast bacterium that often manifests as pulmonary infection since the primary route of entry is via the respiratory tract. As an opportunistic organism, Nocardia primarily affects immunocompromised individuals. Infection with Nocardia is uncommon. Primary cutaneous nocardiosis which is caused by percutaneous inoculation is even more rare. Here, we report a case of primary cutaneous nocardiosis in an adolescent with Crohn disease receiving treatment with adalimumab and azathioprine. Early identification and treatment are important to prevent disease progression and to avoid severe complications. Diagnosis is made principally by culture. Given that culture results may take up to two weeks to return, primary cutaneous nocardiosis should be maintained in the differential for any superficial cutaneous infection that arises in individuals undergoing treatment with immunosuppressive agents.http://dx.doi.org/10.1155/2020/1532875 |
| spellingShingle | Steven A. Svoboda Joshua D. Eikenberg Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease Case Reports in Pediatrics |
| title | Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease |
| title_full | Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease |
| title_fullStr | Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease |
| title_full_unstemmed | Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease |
| title_short | Primary Cutaneous Nocardiosis in an Adolescent with Crohn Disease |
| title_sort | primary cutaneous nocardiosis in an adolescent with crohn disease |
| url | http://dx.doi.org/10.1155/2020/1532875 |
| work_keys_str_mv | AT stevenasvoboda primarycutaneousnocardiosisinanadolescentwithcrohndisease AT joshuadeikenberg primarycutaneousnocardiosisinanadolescentwithcrohndisease |