Pharmacological modulation of MRAP2 protein on murine melatonin receptor signaling

Pharmacological modulation of MRAP2 protein on murine melatonin receptor signaling

IntroductionMTNR1A and MTNR1B, crucial for regulating circadian rhythms and various physiological processes, have well- established biological significance. The role of MRAP2, a single transmembrane accessory protein, in modulating the pharmacological activity of melatonin receptors remains unclear...

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Main Authors: Wenqi Song, Yanchuan Li, Hongtao Xu, Yaqun Zhang, Liu Liu, Yihao Li, Xinran Wang, Yueming Du, Yining Chen, Jianjun Lyu, Lingjing Jin, Chao Zhang, Yuchen Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
MTNR1A
MTNR1B
MRAP2
melatonin
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1593345/full
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