Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure

The effects of moderate hydrostatic pressure (MHP) pretreatment on bioactive metabolites in Tartary buckwheat sprouts remain insufficiently studied. In this work, a non-targeted metabolomics approach, combined with feature-based molecular networking (FBMN), identified 22 metabolites in sprouts treat...

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Main Authors: Liangyu Zhang, Shuangyong Ding, Rui Xu, Li Xiao, Jianxiong Chen, Tao Wu, Weili Li
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S259015752500135X
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author Liangyu Zhang
Shuangyong Ding
Rui Xu
Li Xiao
Jianxiong Chen
Tao Wu
Weili Li
author_facet Liangyu Zhang
Shuangyong Ding
Rui Xu
Li Xiao
Jianxiong Chen
Tao Wu
Weili Li
author_sort Liangyu Zhang
collection DOAJ
description The effects of moderate hydrostatic pressure (MHP) pretreatment on bioactive metabolites in Tartary buckwheat sprouts remain insufficiently studied. In this work, a non-targeted metabolomics approach, combined with feature-based molecular networking (FBMN), identified 22 metabolites in sprouts treated with 0–30 MPa pressure, four of which were previously unreported, thus expanding the species' phytochemical diversity. MHP treatment activated phenylalanine ammonia-lyase (PAL), resulting in a 2.3-fold increase in total flavonoids, particularly glycosylated derivatives such as quercetin 3-rutinoside 7-glucoside (13.2-fold increase at 25 MPa). In contrast, condensed tannins, responsible for astringency, were reduced by 40–60 %. These findings suggest that MHP pretreatment may serve as a sustainable alternative to chemical elicitors, promoting biofortification and improving sensory attributes in sprout-based functional foods.
format Article
id doaj-art-32f0f4cce2ff4dc7b81a6272b4efdcab
institution DOAJ
issn 2590-1575
language English
publishDate 2025-02-01
publisher Elsevier
record_format Article
series Food Chemistry: X
spelling doaj-art-32f0f4cce2ff4dc7b81a6272b4efdcab2025-08-20T02:55:29ZengElsevierFood Chemistry: X2590-15752025-02-012610228810.1016/j.fochx.2025.102288Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressureLiangyu Zhang0Shuangyong Ding1Rui Xu2Li Xiao3Jianxiong Chen4Tao Wu5Weili Li6Food Microbiology Key Laboratory of Sichuan Province, Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Xihua University, No.999 Guangchang Road, Chengdu 610039, China.Food Microbiology Key Laboratory of Sichuan Province, Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Xihua University, No.999 Guangchang Road, Chengdu 610039, China.College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao, China.Food Microbiology Key Laboratory of Sichuan Province, Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Xihua University, No.999 Guangchang Road, Chengdu 610039, China.Sichuan Huan Tai Biotechnology Co., Ltd., 979 Konggang 3rd Road, Shuangliu District, Chengdu, Sichuan Province, Chengdu 610000, China.Food Microbiology Key Laboratory of Sichuan Province, Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Xihua University, No.999 Guangchang Road, Chengdu 610039, China.; Corresponding authors:Food Microbiology Key Laboratory of Sichuan Province, Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Xihua University, No.999 Guangchang Road, Chengdu 610039, China.; Corresponding authors:The effects of moderate hydrostatic pressure (MHP) pretreatment on bioactive metabolites in Tartary buckwheat sprouts remain insufficiently studied. In this work, a non-targeted metabolomics approach, combined with feature-based molecular networking (FBMN), identified 22 metabolites in sprouts treated with 0–30 MPa pressure, four of which were previously unreported, thus expanding the species' phytochemical diversity. MHP treatment activated phenylalanine ammonia-lyase (PAL), resulting in a 2.3-fold increase in total flavonoids, particularly glycosylated derivatives such as quercetin 3-rutinoside 7-glucoside (13.2-fold increase at 25 MPa). In contrast, condensed tannins, responsible for astringency, were reduced by 40–60 %. These findings suggest that MHP pretreatment may serve as a sustainable alternative to chemical elicitors, promoting biofortification and improving sensory attributes in sprout-based functional foods.http://www.sciencedirect.com/science/article/pii/S259015752500135XFagopyrum tataricumGerminationFeature-based molecular networkModerate -hydrostatic pressureUHPLC-Q-TOF-MS/MS
spellingShingle Liangyu Zhang
Shuangyong Ding
Rui Xu
Li Xiao
Jianxiong Chen
Tao Wu
Weili Li
Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure
Food Chemistry: X
Fagopyrum tataricum
Germination
Feature-based molecular network
Moderate -hydrostatic pressure
UHPLC-Q-TOF-MS/MS
title Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure
title_full Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure
title_fullStr Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure
title_full_unstemmed Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure
title_short Integrative metabolomics and molecular networking reveal metabolic rewiring in Tartary buckwheat sprouts under moderate hydrostatic pressure
title_sort integrative metabolomics and molecular networking reveal metabolic rewiring in tartary buckwheat sprouts under moderate hydrostatic pressure
topic Fagopyrum tataricum
Germination
Feature-based molecular network
Moderate -hydrostatic pressure
UHPLC-Q-TOF-MS/MS
url http://www.sciencedirect.com/science/article/pii/S259015752500135X
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AT ruixu integrativemetabolomicsandmolecularnetworkingrevealmetabolicrewiringintartarybuckwheatsproutsundermoderatehydrostaticpressure
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