Effect of lncRNA H19 on Rats with Chronic Heart Failure Based on TGF-β1/Smad3 Signaling Pathway

Effect of lncRNA H19 on Rats with Chronic Heart Failure Based on TGF-β1/Smad3 Signaling Pathway

ObjectiveTo explore the effect of long non-coding RNA H19 (lncRNA H19) and microRNA (miRNA)-200a on cardiac function and myocardial fibrosis in rats with chronic heart failure based on transforming growth factor-β1 (TGF-β1)/Smad homolog 3 (Smad3) signaling pathway.MethodsA total of 60 clean grade ad...

Full description

Saved in:

Bibliographic Details
Main Authors:	WANG Lingyan, CAO Guojun, MEI Yang, ZHANG Bin, ZHOU Shijing
Format:	Article
Language:	English
Published:	Editorial Office of Rehabilitation Medicine 2023-12-01
Series:	康复学报
Subjects:	heart failure long non-coding RNA H19 microRNA-200a TGF-β1/Smad3 signaling pathway heart function myocardial fibrosis
Online Access:	http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2023.06008
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

LncRNA PVT1 activated by TGF-β1/Smad3 facilitates proliferation and metastasis of hepatocellular carcinoma via upregulating Smad6 and NRG1
by: Shuaihui Wu, et al.
Published: (2025-05-01)

Expression of individual members of the TGF-β/SMAD signalling pathway in the progression and survival of patients with colorectal carcinoma
by: Ivana Večurkovská, et al.
Published: (2024-11-01)

Environmentally relevant concentration PFNA promotes degradation of SMAD7 to drive progression of ovarian cancer via TGF-β/SMADs signaling pathway
by: Jiamin Zhong, et al.
Published: (2024-10-01)

miR-21 and miR-155 in the regulation of TGF-β1/SMAD signaling pathway of the line breast cancer cells with different metastatic potential
by: Z. N. Nikiphorova, et al.
Published: (2015-09-01)

Aging increases susceptibility to liver fibrosis through enhanced NAT10-mediated ac4C modification of TGFβ1 mRNA
by: Xuyun Peng, et al.
Published: (2025-08-01)

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
by: Qian Huang, et al.
Published: (2022-09-01)

Corrigendum: Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
by: Qian Huang, et al.
Published: (2024-12-01)

Preclinical validation of TGFβ inhibitors as a novel therapeutic strategy for post-traumatic heterotopic ossification
by: Jaira Ferreira de Vasconcellos, et al.
Published: (2025-04-01)

CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism
by: Mian Liu, et al.
Published: (2025-07-01)

SQLE promotes osteosarcoma progression via activating TGFβ/SMAD signaling pathway
by: Qi Song, et al.
Published: (2024-12-01)

Mechanisms of the TGF-β1/Smad3-signaling pathway in gender differences in alcoholic liver fibrosis
by: Xiaomin Hong, et al.
Published: (2024-02-01)

Role of the TGF-β/Smad3 pathway in pancreatic cancer cell growth and stem cell characteristics
by: Yanling Zhang, et al.
Published: (2025-08-01)

Betulinic Acid Inhibits the Metastasis of Colon Cancer Cells through Regulating TGF-β/Smad Signaling Pathway
by: Xiaoying LIN, et al.
Published: (2020-02-01)

The promotive role of reticulocalbin 3 (RCN3) in the pathogenesis of keloid via TGFβ1/Smad2/Smad7 signaling pathway in vitro
by: Wang HongYu, et al.
Published: (2024-12-01)

OTUD3 inhibits breast cancer cell metastasis by regulating TGF-β pathway through deubiquitinating SMAD7
by: Chenchen Geng, et al.
Published: (2025-05-01)

Zhilong Huoxue Tongyu capsule inhibits hypertensive myocardial fibrosis via balancing TGF-β1/Smad3/Erbb4-IR/miR-29b pathway
by: Qiuyu Liu, et al.
Published: (2025-07-01)

Traditional Chinese Medicine targeting the TGF-β/Smad signaling pathway as a potential therapeutic strategy for renal fibrosis
by: Hao Jiao, et al.
Published: (2025-05-01)

CircRALGPS2 modulates chicken follicle development through promotion of granulosa cell apoptosis and autophagy via the miR-200a-3p/TGFβ2/SMAD pathway
by: Haorong He, et al.
Published: (2025-08-01)

Osthole mitigates the myofibroblast properties in oral submucous fibrosis by suppressing the TGF-β/smad2 signaling pathway and NCK-AS1 expression
by: Po-Yu Yang, et al.
Published: (2025-04-01)

RUNX2 mediated epithelial mesenchymal transition induced by TGF beta and Smad signaling promotes malignant progression in glioma
by: Peng Zhou, et al.
Published: (2025-07-01)

UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway
by: Lijie Yang, et al.
Published: (2025-01-01)

Study on the mechanism of Huoxue Lishui compound in treating spontaneous hypertensive rats based on TGF-β1-Smads signaling pathway
by: YANG Shuo, et al.
Published: (2024-08-01)

Exploring the molecular mechanisms and therapeutic potential of SMAD4 in colorectal cancer
by: Hui Shan, et al.
Published: (2024-12-01)

ＴＧＦ－β１／Ｓｍａｄ７信号通路在哈萨克族食管癌上皮间质转化中的作用
Published: (2015-01-01)

RETRACTED: MicroRNA‐425‐3p inhibits myocardial inflammation and cardiomyocyte apoptosis in mice with viral myocarditis through targeting TGF‐β1
by: Junhua Li, et al.
Published: (2021-03-01)

Oroxylin A suppressed colorectal cancer metastasis by inhibiting the activation of the TGF-β/SMAD signal pathway
by: Ji-Ping Cao, et al.
Published: (2024-10-01)

Allicin induced AMPK signaling attenuated Smad3 pathway mediated lung fibrosis
by: Shun Nakazawa, et al.
Published: (2025-05-01)

An intricate role of Ang II/AT1 in the modulation of monosodium glutamate-induced pulmonary fibrosis by TGF-β/Smad through quercetin
by: Arnab Banerjee, et al.
Published: (2025-07-01)

M2-like macrophages derived from THP-1 cells promote myofibroblast differentiation of synovial fibroblasts in association with the TGF-β1/SMAD2/3 signaling pathway
by: Nguyen Tran Canh Tung, et al.
Published: (2025-07-01)

Inhibitory effects of oxyresveratrol on ERK and Smad1/2 phosphorylation and HSC activation in preventing carbon tetrachloride-induced rat liver fibrosis
by: Guliang Yang, et al.
Published: (2021-01-01)

NEK2 promotes colorectal cancer progression by activating the TGF-β/Smad2 signaling pathway
by: Hai Qin, et al.
Published: (2025-01-01)

Lapatinib ameliorates skin fibrosis by inhibiting TGF-β1/Smad and non-Smad signaling pathway
by: Yongping Wang, et al.
Published: (2025-03-01)

Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis
by: Jinhao Xu, et al.
Published: (2024-12-01)

m6A-modified lncRNA GAS5 promotes M1-polarization of microglia in alcohol use disorder
by: Shuang Zhu, et al.
Published: (2025-02-01)

Smad4 and TGFβ1 dependent gene expression signatures in conditional intestinal adenoma, organoids and colorectal cancer
by: Mirvat Surakhy, et al.
Published: (2025-05-01)

Exploration of the mechanism of NORAD activation of TGF-β1/Smad3 through miR-136-5p and promotion of tacrolimus-induced renal fibrosis
by: Lei Liu, et al.
Published: (2023-12-01)

Tricellulin facilitates colorectal cancer metastasis through activation of the TGFβ/SMAD2/3 signalling pathway
by: Wenfang Yang, et al.
Published: (2025-04-01)

Propolis compound inhibits profibrotic TGF-β1/SMAD signalling in human fibroblasts
by: Lisa J. Randall, et al.
Published: (2025-07-01)

Anti-fibrosis effect of astragaloside IV in animal models of cardiovascular diseases and its mechanisms: a systematic review
by: Shiyu Zhang, et al.
Published: (2025-12-01)

HMGA2 Promotes Cellular Proliferation, Invasion and Metastasis of Laryngeal Cancer Through TGF-β/Smad Signaling Pathway
by: Xianxue WEN, et al.
Published: (2025-07-01)