Serum HMGB1 as a diagnostic biomarker and mediator of childhood trauma in adolescent depression
BackgroundAdolescent depression is a global health challenge with increasing rates and long-term impacts on development. Current diagnostics lack objective biomarkers, relying on subjective assessments. Neuroinflammation, particularly High mobility group box 1 (HMGB1), a systemic inflammation mediat...
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| Main Authors: | Jingyue Xiang, Yiqun Qin, Ruhong Jiang, Xiaolan Wang, Yang Zhou, Jia Liu, Li Kuang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1584320/full |
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