Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research
Abstract In the article “Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis”, Weng et al. used ICD-9/ICD-10 codes to define sepsis. However, we suggest that using the Sepsis-3.0 criteria, which incorporates SOFA scoring...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | Journal of Translational Medicine |
| Online Access: | https://doi.org/10.1186/s12967-025-06612-1 |
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| author | Guangdong Wang Yaxin Zhang |
| author_facet | Guangdong Wang Yaxin Zhang |
| author_sort | Guangdong Wang |
| collection | DOAJ |
| description | Abstract In the article “Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis”, Weng et al. used ICD-9/ICD-10 codes to define sepsis. However, we suggest that using the Sepsis-3.0 criteria, which incorporates SOFA scoring and infection evidence, would provide a more accurate diagnosis. The MIMIC-IV database offers a derived table based on Sepsis-3.0, which could improve cohort definition and enhance the study’s clinical relevance. We recommend that future research adopt Sepsis-3.0 or perform sensitivity analyses to improve result robustness. |
| format | Article |
| id | doaj-art-32e52d11b83e42fa8f2865fd50608ba6 |
| institution | Kabale University |
| issn | 1479-5876 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj-art-32e52d11b83e42fa8f2865fd50608ba62025-08-20T03:43:02ZengBMCJournal of Translational Medicine1479-58762025-07-012311210.1186/s12967-025-06612-1Concerns regarding sepsis identification using ICD codes in MIMIC-IV based researchGuangdong Wang0Yaxin Zhang1Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Xi’an Jiaotong UniversityDepartment of Neurology, Xiamen Humanity Hospital, Fujian Medical UniversityAbstract In the article “Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis”, Weng et al. used ICD-9/ICD-10 codes to define sepsis. However, we suggest that using the Sepsis-3.0 criteria, which incorporates SOFA scoring and infection evidence, would provide a more accurate diagnosis. The MIMIC-IV database offers a derived table based on Sepsis-3.0, which could improve cohort definition and enhance the study’s clinical relevance. We recommend that future research adopt Sepsis-3.0 or perform sensitivity analyses to improve result robustness.https://doi.org/10.1186/s12967-025-06612-1 |
| spellingShingle | Guangdong Wang Yaxin Zhang Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research Journal of Translational Medicine |
| title | Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research |
| title_full | Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research |
| title_fullStr | Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research |
| title_full_unstemmed | Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research |
| title_short | Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research |
| title_sort | concerns regarding sepsis identification using icd codes in mimic iv based research |
| url | https://doi.org/10.1186/s12967-025-06612-1 |
| work_keys_str_mv | AT guangdongwang concernsregardingsepsisidentificationusingicdcodesinmimicivbasedresearch AT yaxinzhang concernsregardingsepsisidentificationusingicdcodesinmimicivbasedresearch |