Concerns regarding sepsis identification using ICD codes in MIMIC-IV based research
Abstract In the article “Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis”, Weng et al. used ICD-9/ICD-10 codes to define sepsis. However, we suggest that using the Sepsis-3.0 criteria, which incorporates SOFA scoring...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Journal of Translational Medicine |
| Online Access: | https://doi.org/10.1186/s12967-025-06612-1 |
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| Summary: | Abstract In the article “Comparison of rhythm and rate control medications for new-onset atrial fibrillation in septic patients: MIMIC-IV database analysis”, Weng et al. used ICD-9/ICD-10 codes to define sepsis. However, we suggest that using the Sepsis-3.0 criteria, which incorporates SOFA scoring and infection evidence, would provide a more accurate diagnosis. The MIMIC-IV database offers a derived table based on Sepsis-3.0, which could improve cohort definition and enhance the study’s clinical relevance. We recommend that future research adopt Sepsis-3.0 or perform sensitivity analyses to improve result robustness. |
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| ISSN: | 1479-5876 |