Investigating a new generation of ribozymes in order to target HCV.
For a long time nucleic acid-based approaches directed towards controlling the propagation of Hepatitis C Virus (HCV) have been considered to possess high potential. Towards this end, ribozymes (i.e. RNA enzymes) that specifically recognize and subsequently catalyze the cleavage of their RNA substra...
Saved in:
| Main Authors: | Michel V Lévesque, Dominique Lévesque, Francis P Brière, Jean-Pierre Perreault |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-03-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009627&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A modern mode of activation for nucleic acid enzymes.
by: Dominique Lévesque, et al.
Published: (2007-07-01) -
A novel ribozyme-based prophylaxis inhibits influenza A virus replication and protects from severe disease.
by: Julie Motard, et al.
Published: (2011-01-01) -
Exploring the space of self-reproducing ribozymes using generative models
by: Camille N. Lambert, et al.
Published: (2025-08-01) -
Decoupling Global and Local Structural Changes in Self-aminoacylating Ribozymes Reveals the Critical Role of Local Structural Dynamics in Ribozyme Activity
by: Yu-Kai Cheng, et al.
Published: (2025-05-01) -
Inducible knockdown of Plasmodium gene expression using the glmS ribozyme.
by: Parichat Prommana, et al.
Published: (2013-01-01)