Erioflorin and Erioflorin Acetate Induce Cell Death in Advanced Prostate Cancer Through ROS Increase and NF-κB Inhibition

Erioflorin and Erioflorin Acetate Induce Cell Death in Advanced Prostate Cancer Through ROS Increase and NF-κB Inhibition

Germacranes are a type of sesquiterpene lactones with anti-inflammatory and cytotoxic properties against cancer cell lines. In this in vitro study, erioflorin and erioflorin acetate were isolated and purified from the leaves of <i>Podanthus mitiqui</i> Lindl (Mitique or Mitriu), a shrub...

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Bibliographic Details
Main Authors: Cecilia Villegas, Iván González-Chavarría, Viviana Burgos, Jaime R. Cabrera-Pardo, Bernd Schmidt, Cristian Paz
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Journal of Xenobiotics
Subjects:
<i>Podanthus mitiqui</i>
prostate cancer
erioflorin
NF-κB signaling
cytotoxicity
germacrane sesquiterpene lactones
Online Access:https://www.mdpi.com/2039-4713/15/2/45
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