From Inflammation to Current and Alternative Therapies Involved in Wound Healing
Wound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators fr...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
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| Series: | International Journal of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2017/3406215 |
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| _version_ | 1832548389199282176 |
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| author | Mariana Barreto Serra Wermerson Assunção Barroso Neemias Neves da Silva Selma do Nascimento Silva Antonio Carlos Romão Borges Iracelle Carvalho Abreu Marilene Oliveira da Rocha Borges |
| author_facet | Mariana Barreto Serra Wermerson Assunção Barroso Neemias Neves da Silva Selma do Nascimento Silva Antonio Carlos Romão Borges Iracelle Carvalho Abreu Marilene Oliveira da Rocha Borges |
| author_sort | Mariana Barreto Serra |
| collection | DOAJ |
| description | Wound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators from cells to perform regulatory events. In this article, we will review the pathway in the skin healing cascade, relating the major chemical inflammatory mediators, cellular and molecular, as well as demonstrating the local and systemic factors that interfere in healing and disorders associated with tissue repair deficiency. Finally, we will discuss the current therapeutic interventions in the wounds treatment, and the alternative therapies used as promising results in the development of new products with healing potential. |
| format | Article |
| id | doaj-art-32d15ced80044b1f90e9facbb6802287 |
| institution | Kabale University |
| issn | 2090-8040 2042-0099 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Inflammation |
| spelling | doaj-art-32d15ced80044b1f90e9facbb68022872025-02-03T06:14:11ZengWileyInternational Journal of Inflammation2090-80402042-00992017-01-01201710.1155/2017/34062153406215From Inflammation to Current and Alternative Therapies Involved in Wound HealingMariana Barreto Serra0Wermerson Assunção Barroso1Neemias Neves da Silva2Selma do Nascimento Silva3Antonio Carlos Romão Borges4Iracelle Carvalho Abreu5Marilene Oliveira da Rocha Borges6Physiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilWound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators from cells to perform regulatory events. In this article, we will review the pathway in the skin healing cascade, relating the major chemical inflammatory mediators, cellular and molecular, as well as demonstrating the local and systemic factors that interfere in healing and disorders associated with tissue repair deficiency. Finally, we will discuss the current therapeutic interventions in the wounds treatment, and the alternative therapies used as promising results in the development of new products with healing potential.http://dx.doi.org/10.1155/2017/3406215 |
| spellingShingle | Mariana Barreto Serra Wermerson Assunção Barroso Neemias Neves da Silva Selma do Nascimento Silva Antonio Carlos Romão Borges Iracelle Carvalho Abreu Marilene Oliveira da Rocha Borges From Inflammation to Current and Alternative Therapies Involved in Wound Healing International Journal of Inflammation |
| title | From Inflammation to Current and Alternative Therapies Involved in Wound Healing |
| title_full | From Inflammation to Current and Alternative Therapies Involved in Wound Healing |
| title_fullStr | From Inflammation to Current and Alternative Therapies Involved in Wound Healing |
| title_full_unstemmed | From Inflammation to Current and Alternative Therapies Involved in Wound Healing |
| title_short | From Inflammation to Current and Alternative Therapies Involved in Wound Healing |
| title_sort | from inflammation to current and alternative therapies involved in wound healing |
| url | http://dx.doi.org/10.1155/2017/3406215 |
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