Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)

The skin and its products, such as the mucus, represent an important defense mechanism against infection by pathogens. Various environmental conditions can alter mucus composition and/or cells embedded in this matrix. The analysis of skin mucus is considered a useful method to evaluate the biologica...

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Main Authors: Enrico Volpe, Sara Ciulli, Maria Morini, Laura Gentile, Antonio Casalini, Chiara Gentilezza, Luciana Mandrioli
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/12/1810
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author Enrico Volpe
Sara Ciulli
Maria Morini
Laura Gentile
Antonio Casalini
Chiara Gentilezza
Luciana Mandrioli
author_facet Enrico Volpe
Sara Ciulli
Maria Morini
Laura Gentile
Antonio Casalini
Chiara Gentilezza
Luciana Mandrioli
author_sort Enrico Volpe
collection DOAJ
description The skin and its products, such as the mucus, represent an important defense mechanism against infection by pathogens. Various environmental conditions can alter mucus composition and/or cells embedded in this matrix. The analysis of skin mucus is considered a useful method to evaluate the biological response of fish to stimuli. The mucus and cells can be considered suitable non-invasive biomarkers. With this preliminary study, an antibacterial capacity method was applied to cutaneous mucus samples of a European eel population. This standardized method highlighted the ability of the mucus to significantly counteract the proliferation of two bacteria, the opportunistic pathogen <i>Aeromonas hydrophila</i> and the primary pathogen <i>Aeromonas salmonicida</i>. The cytological method using skin scraping has proven to be a useful non-invasive tool, having allowed the highlighting of the two most represented cellular populations of the cutaneous covering, the epidermal cells and the goblet cells, in combination with mucous strands. Cytological findings did not disclose pathologic elements in the mucus. A broader use of these two non-invasive microbiological and cytological methods can provide useful information on fish health, indirectly contributing to the conservation of the species.
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spelling doaj-art-32cfaaad21f44e36b6906d356ea73f792025-08-20T02:24:34ZengMDPI AGAnimals2076-26152025-06-011512181010.3390/ani15121810Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)Enrico Volpe0Sara Ciulli1Maria Morini2Laura Gentile3Antonio Casalini4Chiara Gentilezza5Luciana Mandrioli6Department of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyDepartment of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyDepartment of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyDepartment of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyDepartment of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyDepartment of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyDepartment of Veterinary Medical Sciences, Alma Mater Studiorum University of Bologna, 40064 Bologna, ItalyThe skin and its products, such as the mucus, represent an important defense mechanism against infection by pathogens. Various environmental conditions can alter mucus composition and/or cells embedded in this matrix. The analysis of skin mucus is considered a useful method to evaluate the biological response of fish to stimuli. The mucus and cells can be considered suitable non-invasive biomarkers. With this preliminary study, an antibacterial capacity method was applied to cutaneous mucus samples of a European eel population. This standardized method highlighted the ability of the mucus to significantly counteract the proliferation of two bacteria, the opportunistic pathogen <i>Aeromonas hydrophila</i> and the primary pathogen <i>Aeromonas salmonicida</i>. The cytological method using skin scraping has proven to be a useful non-invasive tool, having allowed the highlighting of the two most represented cellular populations of the cutaneous covering, the epidermal cells and the goblet cells, in combination with mucous strands. Cytological findings did not disclose pathologic elements in the mucus. A broader use of these two non-invasive microbiological and cytological methods can provide useful information on fish health, indirectly contributing to the conservation of the species.https://www.mdpi.com/2076-2615/15/12/1810antibacterial assay<i>Aeromonas</i> sp.cytological analysisepidermisEuropean eel<i>Anguilla anguilla</i>
spellingShingle Enrico Volpe
Sara Ciulli
Maria Morini
Laura Gentile
Antonio Casalini
Chiara Gentilezza
Luciana Mandrioli
Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)
Animals
antibacterial assay
<i>Aeromonas</i> sp.
cytological analysis
epidermis
European eel
<i>Anguilla anguilla</i>
title Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)
title_full Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)
title_fullStr Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)
title_full_unstemmed Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)
title_short Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (<i>Anguilla anguilla,</i> Linnaeus 1758)
title_sort preliminary study of the antimicrobial capacity of the cutaneous mucus and smear cytology of the epidermis in a population of european eels i anguilla anguilla i linnaeus 1758
topic antibacterial assay
<i>Aeromonas</i> sp.
cytological analysis
epidermis
European eel
<i>Anguilla anguilla</i>
url https://www.mdpi.com/2076-2615/15/12/1810
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