Multiple Organ Dysfunction After Cardiosurgical Interventions

Objective: to study the clinical efficiency of introducing an algorithm for organ-protective intensive care. Materials and methods. 3278 case histories of patients admitted to the clinic in 2000—2009 for surgical treatment (under extracorporeal circulation) for coronary heart disease (CHD) and acqui...

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Main Authors: L. S. Barbarash, Ye. V. Grigoryev, G. P. Plotnikov, B. L, Hayes, G. V. Moiseyenkov, D. L. Shukevich, S. V. Ivanov, Yu. N. Odarenko
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2010-10-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/388
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author L. S. Barbarash
Ye. V. Grigoryev
G. P. Plotnikov
B. L, Hayes
G. V. Moiseyenkov
D. L. Shukevich
S. V. Ivanov
Yu. N. Odarenko
author_facet L. S. Barbarash
Ye. V. Grigoryev
G. P. Plotnikov
B. L, Hayes
G. V. Moiseyenkov
D. L. Shukevich
S. V. Ivanov
Yu. N. Odarenko
author_sort L. S. Barbarash
collection DOAJ
description Objective: to study the clinical efficiency of introducing an algorithm for organ-protective intensive care. Materials and methods. 3278 case histories of patients admitted to the clinic in 2000—2009 for surgical treatment (under extracorporeal circulation) for coronary heart disease (CHD) and acquired heart defects (AHD) were retrospectively analyzed. Throughout the analyzed period, the patients operated on for CHD and AHD were 2068 (63.1%) and 1210 (36.9%), respectively; the postoperative incidence of multiple organ dysfunction (MOD) among all the patients was 11.8% (378 patients); mortality in MOD was 3.75% (n=123) of the operated patients (included into the study) or 32.5% of all the patients with MOD. Conclusion. The incidence of MOD is in proportion to the number of surgical interventions and depends on their specific features (recurrence, baseline severity, comorbidity, or multifocal atherosclerosis). Preventive intensive therapy for MOD reduced mortality and altered its syndromic pattern towards a preponderance of pyoseptic complications. Key words: cardiosurgery, extracorporeal circulation, multiple organ dysfunction.
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spelling doaj-art-32cd2a72c124495b8c2c1abbf3ebab142025-08-20T03:18:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102010-10-016510.15360/1813-9779-2010-5-31388Multiple Organ Dysfunction After Cardiosurgical InterventionsL. S. BarbarashYe. V. GrigoryevG. P. PlotnikovB. L, HayesG. V. MoiseyenkovD. L. ShukevichS. V. IvanovYu. N. OdarenkoObjective: to study the clinical efficiency of introducing an algorithm for organ-protective intensive care. Materials and methods. 3278 case histories of patients admitted to the clinic in 2000—2009 for surgical treatment (under extracorporeal circulation) for coronary heart disease (CHD) and acquired heart defects (AHD) were retrospectively analyzed. Throughout the analyzed period, the patients operated on for CHD and AHD were 2068 (63.1%) and 1210 (36.9%), respectively; the postoperative incidence of multiple organ dysfunction (MOD) among all the patients was 11.8% (378 patients); mortality in MOD was 3.75% (n=123) of the operated patients (included into the study) or 32.5% of all the patients with MOD. Conclusion. The incidence of MOD is in proportion to the number of surgical interventions and depends on their specific features (recurrence, baseline severity, comorbidity, or multifocal atherosclerosis). Preventive intensive therapy for MOD reduced mortality and altered its syndromic pattern towards a preponderance of pyoseptic complications. Key words: cardiosurgery, extracorporeal circulation, multiple organ dysfunction.https://www.reanimatology.com/rmt/article/view/388
spellingShingle L. S. Barbarash
Ye. V. Grigoryev
G. P. Plotnikov
B. L, Hayes
G. V. Moiseyenkov
D. L. Shukevich
S. V. Ivanov
Yu. N. Odarenko
Multiple Organ Dysfunction After Cardiosurgical Interventions
Общая реаниматология
title Multiple Organ Dysfunction After Cardiosurgical Interventions
title_full Multiple Organ Dysfunction After Cardiosurgical Interventions
title_fullStr Multiple Organ Dysfunction After Cardiosurgical Interventions
title_full_unstemmed Multiple Organ Dysfunction After Cardiosurgical Interventions
title_short Multiple Organ Dysfunction After Cardiosurgical Interventions
title_sort multiple organ dysfunction after cardiosurgical interventions
url https://www.reanimatology.com/rmt/article/view/388
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AT dlshukevich multipleorgandysfunctionaftercardiosurgicalinterventions
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