Patient derived cancer-associated fibroblasts from non-small cell lung cancer undergo phenotypic drift in culture

Abstract Background Cancer-associated fibroblasts (CAFs) are the predominant cell type in the stroma of many solid organ malignancies, including non-small cell lung cancer (NSCLC). They exhibit considerable phenotypic and functional heterogeneity and are widely used in functional assays and co-cultu...

Full description

Saved in:
Bibliographic Details
Main Authors: Layla Mathieson, Phoebe Jones, Lilian Koppensteiner, Liam Neilson, David A. Dorward, Richard O’Connor, Ahsan R. Akram
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:BJC Reports
Online Access:https://doi.org/10.1038/s44276-025-00159-w
Tags: Add Tag
No Tags, Be the first to tag this record!