Differential effects of acute and chronic treatment with the flavonoid chrysin on anxiety-like behavior and Fos immunoreactivity in the lateral septal nucleus in rats

Differential effects of acute and chronic treatment with the flavonoid chrysin on anxiety-like behavior and Fos immunoreactivity in the lateral septal nucleus in rats

The aim of this study was to compare the effects of acute (a single injection) and chronic (21 consecutive days) treatments with chrysin 2, 4, and 8 μmol kg−1 on anxiety-like behavior and Fos immunoreactivity in the lateral septum nucleus (LSN), a structure that is involved in the regulation of anxi...

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Bibliographic Details
Main Authors: Germán-Ponciano León Jesús, Puga-Olguín Abraham, De Jesús Rovirosa-Hernández María, Caba Mario, Meza Enrique, Rodríguez-Landa Juan Francisco
Format: Article
Language:English
Published: Sciendo 2020-09-01
Series:Acta Pharmaceutica
Subjects:
chrysin
anxiolytic
elevated plus maze
fos protein
lateral septal nucleus
Online Access:https://doi.org/10.2478/acph-2020-0022
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