Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data

Meningococcal infection (MI) is one of the heaviest illnesses with specific clinical picture and outcomes. MI prophylaxis is also actual from a social-economic viewpoint. Analysis based on RWD is important and should include epidemiological, medical, regional economic parameters as well as demographi...

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Main Authors: S. V. Svetlichnaya, L. A. Elagina, L. D. Popovich
Format: Article
Language:Russian
Published: Publishing House OKI 2023-08-01
Series:Реальная клиническая практика: данные и доказательства
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Online Access:https://www.myrwd.ru/jour/article/view/39
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author S. V. Svetlichnaya
L. A. Elagina
L. D. Popovich
author_facet S. V. Svetlichnaya
L. A. Elagina
L. D. Popovich
author_sort S. V. Svetlichnaya
collection DOAJ
description Meningococcal infection (MI) is one of the heaviest illnesses with specific clinical picture and outcomes. MI prophylaxis is also actual from a social-economic viewpoint. Analysis based on RWD is important and should include epidemiological, medical, regional economic parameters as well as demographic data.Aim: economic evaluation of the potential outcomes of vaccination against MI in Far East Federal District of Russia (FER) in frames of vaccination growth in children.Materials and methods: Modelling of epidemiological and economic outcomes of MI vaccination with MenACWY-D vaccine in 95% of 3-year-old children in FER. Economic model usage cost vaccination, its efficacy, morbidity after vaccine usage, and mortality with such kind of parameters comparison w/o vaccination. The economic gain of vaccination is calculated in terms of the prevented loss of life years and the monetary equivalent of the per capita domestic regional product.Results: Vaccination against MI in 100 thousand children aged 3 years will decrease morbidity by 64,5% and mortality by 75% during 8 years after vaccination. Social gain is 5,8 mln RUR due to morbidity decrease and 1,3 bln RUR due to saving lives.Conclusion: Vaccination has an economic advantage — benefit after 100 thousand children vaccination up to 4,3 times higher than cost of vaccination in FER.
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institution Kabale University
issn 2782-3784
language Russian
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publisher Publishing House OKI
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series Реальная клиническая практика: данные и доказательства
spelling doaj-art-32bf677cf18e4830b50a9493b0ba0fbe2025-08-20T03:42:26ZrusPublishing House OKIРеальная клиническая практика: данные и доказательства2782-37842023-08-0132314110.37489/2782-3784-myrwd-3437Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological dataS. V. Svetlichnaya0L. A. Elagina1L. D. Popovich2Independent Institute for Social Innovations (IISI)Independent Institute for Social Innovations (IISI)National Research University “Higher Scholl of Economics”Meningococcal infection (MI) is one of the heaviest illnesses with specific clinical picture and outcomes. MI prophylaxis is also actual from a social-economic viewpoint. Analysis based on RWD is important and should include epidemiological, medical, regional economic parameters as well as demographic data.Aim: economic evaluation of the potential outcomes of vaccination against MI in Far East Federal District of Russia (FER) in frames of vaccination growth in children.Materials and methods: Modelling of epidemiological and economic outcomes of MI vaccination with MenACWY-D vaccine in 95% of 3-year-old children in FER. Economic model usage cost vaccination, its efficacy, morbidity after vaccine usage, and mortality with such kind of parameters comparison w/o vaccination. The economic gain of vaccination is calculated in terms of the prevented loss of life years and the monetary equivalent of the per capita domestic regional product.Results: Vaccination against MI in 100 thousand children aged 3 years will decrease morbidity by 64,5% and mortality by 75% during 8 years after vaccination. Social gain is 5,8 mln RUR due to morbidity decrease and 1,3 bln RUR due to saving lives.Conclusion: Vaccination has an economic advantage — benefit after 100 thousand children vaccination up to 4,3 times higher than cost of vaccination in FER.https://www.myrwd.ru/jour/article/view/39meningococcal infectionvaccinationeconomic analysisrwd
spellingShingle S. V. Svetlichnaya
L. A. Elagina
L. D. Popovich
Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
Реальная клиническая практика: данные и доказательства
meningococcal infection
vaccination
economic analysis
rwd
title Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
title_full Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
title_fullStr Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
title_full_unstemmed Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
title_short Evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
title_sort evaluation of the potential economic effects in the increased vaccination against meningococcal infection based on real epidemiological data
topic meningococcal infection
vaccination
economic analysis
rwd
url https://www.myrwd.ru/jour/article/view/39
work_keys_str_mv AT svsvetlichnaya evaluationofthepotentialeconomiceffectsintheincreasedvaccinationagainstmeningococcalinfectionbasedonrealepidemiologicaldata
AT laelagina evaluationofthepotentialeconomiceffectsintheincreasedvaccinationagainstmeningococcalinfectionbasedonrealepidemiologicaldata
AT ldpopovich evaluationofthepotentialeconomiceffectsintheincreasedvaccinationagainstmeningococcalinfectionbasedonrealepidemiologicaldata