A Rare Case of Paraneoplastic Dermatomyositis in a Patient With Metastatic Endometrial Cancer

Dermatomyositis (DM) is a rare autoimmune myopathy that presents with muscle weakness and characteristic skin manifestations. Certain malignancies are associated with DM, such as stomach, colorectal, ovarian, lung, pancreatic, and non-Hodgkin lymphoma. However, there are only rare reports of endomet...

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Bibliographic Details
Main Authors: Parnia Khamooshi, Mavi Rivera Pavon, Cyra Kang-Yoonsun, Viviana Reyes Pinzon, Augustine Mathew Manadan
Format: Article
Language:English
Published: American College of Physicians 2022-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.0480
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Summary:Dermatomyositis (DM) is a rare autoimmune myopathy that presents with muscle weakness and characteristic skin manifestations. Certain malignancies are associated with DM, such as stomach, colorectal, ovarian, lung, pancreatic, and non-Hodgkin lymphoma. However, there are only rare reports of endometrial cancer with DM. In this report, we describe a case of anti–TIF-1-gamma and anti-Mi-2 antibody positive DM in a patient with stage IV endometrial cancer. This case illustrates the importance of considering DM as a paraneoplastic syndrome regardless of both stage and type of malignancy.
ISSN:2767-7664