Hispanic representation in diabetes cardiovascular outcomes trials
Objective To examine Hispanic/Latino representation in diabetes cardiovascular outcomes trials for novel antidiabetic drugs.Research design and methods We compared Hispanic/Latino representation, age, gender and body mass index in diabetes cardiovascular outcomes trials published from January 2008 t...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2019-05-01
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| Series: | BMJ Open Diabetes Research & Care |
| Online Access: | https://drc.bmj.com/content/7/1/e000656.full |
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| _version_ | 1850110052435755008 |
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| author | A. Taylor Kelley Kara Mizokami-Stout Matthew J. O'Brien Michael E. Bowen Jeremy Sussman |
| author_facet | A. Taylor Kelley Kara Mizokami-Stout Matthew J. O'Brien Michael E. Bowen Jeremy Sussman |
| author_sort | A. Taylor Kelley |
| collection | DOAJ |
| description | Objective To examine Hispanic/Latino representation in diabetes cardiovascular outcomes trials for novel antidiabetic drugs.Research design and methods We compared Hispanic/Latino representation, age, gender and body mass index in diabetes cardiovascular outcomes trials published from January 2008 to October 2018 to Hispanic adults with diabetes in the National Health Examination and Nutrition Survey over the same time period.Results Hispanics/Latinos comprised 18.5 % of trial subjects, which was similar to the proportion of US adults with diabetes who identify as Hispanic. Trial subjects were significantly younger, more likely to be female, and more obese than US Hispanics/Latinos. At least 10 different Latin American countries and territories were represented across the 10 trials.Conclusions US Hispanics/Latinos differ from subjects in diabetes cardiovascular outcomes trials, which may limit generalizability of trial results. |
| format | Article |
| id | doaj-art-32abf4c4013146e6ae7cd16992e25d21 |
| institution | OA Journals |
| issn | 2052-4897 |
| language | English |
| publishDate | 2019-05-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Diabetes Research & Care |
| spelling | doaj-art-32abf4c4013146e6ae7cd16992e25d212025-08-20T02:37:55ZengBMJ Publishing GroupBMJ Open Diabetes Research & Care2052-48972019-05-017110.1136/bmjdrc-2019-000656Hispanic representation in diabetes cardiovascular outcomes trialsA. Taylor Kelley0Kara Mizokami-Stout1Matthew J. O'Brien2Michael E. Bowen3Jeremy Sussman4Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USADepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USADivision of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USADepartments of Internal Medicine, Pediatrics and Population and Data Sciences, UT Southwestern Medical Center, Dallas, Texas, USADepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USAObjective To examine Hispanic/Latino representation in diabetes cardiovascular outcomes trials for novel antidiabetic drugs.Research design and methods We compared Hispanic/Latino representation, age, gender and body mass index in diabetes cardiovascular outcomes trials published from January 2008 to October 2018 to Hispanic adults with diabetes in the National Health Examination and Nutrition Survey over the same time period.Results Hispanics/Latinos comprised 18.5 % of trial subjects, which was similar to the proportion of US adults with diabetes who identify as Hispanic. Trial subjects were significantly younger, more likely to be female, and more obese than US Hispanics/Latinos. At least 10 different Latin American countries and territories were represented across the 10 trials.Conclusions US Hispanics/Latinos differ from subjects in diabetes cardiovascular outcomes trials, which may limit generalizability of trial results.https://drc.bmj.com/content/7/1/e000656.full |
| spellingShingle | A. Taylor Kelley Kara Mizokami-Stout Matthew J. O'Brien Michael E. Bowen Jeremy Sussman Hispanic representation in diabetes cardiovascular outcomes trials BMJ Open Diabetes Research & Care |
| title | Hispanic representation in diabetes cardiovascular outcomes trials |
| title_full | Hispanic representation in diabetes cardiovascular outcomes trials |
| title_fullStr | Hispanic representation in diabetes cardiovascular outcomes trials |
| title_full_unstemmed | Hispanic representation in diabetes cardiovascular outcomes trials |
| title_short | Hispanic representation in diabetes cardiovascular outcomes trials |
| title_sort | hispanic representation in diabetes cardiovascular outcomes trials |
| url | https://drc.bmj.com/content/7/1/e000656.full |
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