Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods
Non-destructive control of cefuroxime in tablet medicines without opening the blister pack by measuring the intensity of diff use refl ectance of infrared radiation has been proposed. Near-infrared Fourier transform spectroscopy and digital color spectroscopy using a smartphone and a 3D-printed devi...
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| Format: | Article |
| Language: | English |
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Saratov State University
2025-03-01
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| Series: | Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология |
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| Online Access: | https://ichbe.sgu.ru/sites/ichbe.sgu.ru/files/text-pdf/2025/04/himiya_2025_1-34-41.pdf |
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| _version_ | 1849225463205986304 |
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| author | Amelin, Vasiliy G. Emelyanov, Oleg E. |
| author_facet | Amelin, Vasiliy G. Emelyanov, Oleg E. |
| author_sort | Amelin, Vasiliy G. |
| collection | DOAJ |
| description | Non-destructive control of cefuroxime in tablet medicines without opening the blister pack by measuring the intensity of diff use refl ectance of infrared radiation has been proposed. Near-infrared Fourier transform spectroscopy and digital color spectroscopy using a smartphone and a 3D-printed device have been applied. The data set has been processed by principal component methods, hierarchical cluster analysis and partial least squares regression. The application of chemometric algorithms to determine the concentration of the active ingredient cefuroxime in the drug Zinnat has been considered. The methods of infrared spectroscopy and colorometry have showed comparable results in terms of accuracy in determining the concentration of active ingredient in tablets without opening the blister pack. |
| format | Article |
| id | doaj-art-329f299c41d84bec82a3a7d25de4555e |
| institution | Kabale University |
| issn | 1816-9775 2541-8971 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Saratov State University |
| record_format | Article |
| series | Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология |
| spelling | doaj-art-329f299c41d84bec82a3a7d25de4555e2025-08-24T15:01:35ZengSaratov State UniversityИзвестия Саратовского университета. Новая серия: Серия Химия. Биология. Экология1816-97752541-89712025-03-01251344110.18500/1816-9775-2025-25-1-34-41Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methodsAmelin, Vasiliy G.0Emelyanov, Oleg E.1Vladimir State University named after Alexander and Nikolay Stoletovs, 87, Gorkiy Str., Vladimir, 60000, RussiaVladimir State University named after Alexander and Nikolay Stoletovs, 87, Gorkiy Str., Vladimir, 60000, RussiaNon-destructive control of cefuroxime in tablet medicines without opening the blister pack by measuring the intensity of diff use refl ectance of infrared radiation has been proposed. Near-infrared Fourier transform spectroscopy and digital color spectroscopy using a smartphone and a 3D-printed device have been applied. The data set has been processed by principal component methods, hierarchical cluster analysis and partial least squares regression. The application of chemometric algorithms to determine the concentration of the active ingredient cefuroxime in the drug Zinnat has been considered. The methods of infrared spectroscopy and colorometry have showed comparable results in terms of accuracy in determining the concentration of active ingredient in tablets without opening the blister pack.https://ichbe.sgu.ru/sites/ichbe.sgu.ru/files/text-pdf/2025/04/himiya_2025_1-34-41.pdfcefuroximenondestructive testingdigital colorimetryinfrared spectroscopysmartphone |
| spellingShingle | Amelin, Vasiliy G. Emelyanov, Oleg E. Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология cefuroxime nondestructive testing digital colorimetry infrared spectroscopy smartphone |
| title | Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods |
| title_full | Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods |
| title_fullStr | Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods |
| title_full_unstemmed | Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods |
| title_short | Non-destructive control of tablet forms of cefuroxime by near-infrared spectroscopy and digital colorometry methods |
| title_sort | non destructive control of tablet forms of cefuroxime by near infrared spectroscopy and digital colorometry methods |
| topic | cefuroxime nondestructive testing digital colorimetry infrared spectroscopy smartphone |
| url | https://ichbe.sgu.ru/sites/ichbe.sgu.ru/files/text-pdf/2025/04/himiya_2025_1-34-41.pdf |
| work_keys_str_mv | AT amelinvasiliyg nondestructivecontroloftabletformsofcefuroximebynearinfraredspectroscopyanddigitalcolorometrymethods AT emelyanovolege nondestructivecontroloftabletformsofcefuroximebynearinfraredspectroscopyanddigitalcolorometrymethods |