Study of the Pharmaceutical Grade Polymers effect on the Dissolution of Practically Insoluble Antiretroviral Substances

Study of the Pharmaceutical Grade Polymers effect on the Dissolution of Practically Insoluble Antiretroviral Substances

Introduction. Many of new active pharmaceutical ingredients (APIs) have low solubility that can affect bioavailability negatively and therefore therapeutically efficacy as well. These APIs include the following antiretroviral substances: ritonavir, efavirenz, etravirine. There are various approaches...

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Bibliographic Details
Main Authors: S. A. Zolotov, N. B. Demina, E. S. Ponomarev, I. A. Dain, A. S. Zolotova
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2022-05-01
Series:Разработка и регистрация лекарственных средств
Subjects:
ritonavir
efavirenz
etravirine
dissolution
excipients
polymers
Online Access:https://www.pharmjournal.ru/jour/article/view/1221
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