Megakaryocyte contribution to bone marrow fibrosis: many arrows in the quiver

In Primary Myelofibrosis (PMF), megakaryocyte dysplasia/hyperplasia determines the release of inflammatory cytokines that, in turn, stimulate stromal cells and induce bone marrow fibrosis. The pathogenic mechanism and the cells responsible for progression to bone marrow fibrosis in PMF are not compl...

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Bibliographic Details
Main Authors: Alessandro Malara, Vittorio Abbonante, Maria Zingariello, Anna Rita Franco Migliaccio, Alessandra Balduini
Format: Article
Language:English
Published: PAGEPress Publications 2018-11-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
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Online Access:https://www.mjhid.org/index.php/mjhid/article/view/3629
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