Miyako <i>Bidens pilosa</i> Extract Ameliorates Allodynia and Suppresses Spinal Microglial Activation in Mice with Partial Sciatic Nerve Ligation

Miyako <i>Bidens pilosa</i> Extract Ameliorates Allodynia and Suppresses Spinal Microglial Activation in Mice with Partial Sciatic Nerve Ligation

Neuropathic pain, characterized by chronic allodynia, remains difficult to manage with current pharmacotherapies. Microglial activation plays a pivotal role in the development and maintenance of neuropathic pain and represents a promising therapeutic target. We previously demonstrated that Miyako &l...

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Bibliographic Details
Main Authors: Ai Takahashi, Hiroko Miyagishi, Komugi Tsuruta, Hiroshi Nango, Dai Hirose, Yuri Aono, Minoru Tanigawa, Katsushi Nishimura, Minoru Saito, Takayuki Kawato, Tadashi Saigusa, Yasuhiro Kosuge
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Current Issues in Molecular Biology
Subjects:
neuropathic pain
Miyako <i>Bidens pilosa</i>
microglia
lumbar spinal cord
Online Access:https://www.mdpi.com/1467-3045/47/6/453
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