Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome

Evaluation of bone marrow cytogenetic abnormalities in myelodysplastic syndrome is of great importance for confirming the clonal disease nature, determining the prognosis and choosing treatment tactics. Cytogenetic abnormalities are detected in 40–70 % of patients with myelodysplastic syndrome, and...

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Main Authors: M. N. Pautova, L. E. Koloskova, O. I. Filippova, A. V. Koloskov
Format: Article
Language:Russian
Published: ABV-press 2024-09-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/947
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author M. N. Pautova
L. E. Koloskova
O. I. Filippova
A. V. Koloskov
author_facet M. N. Pautova
L. E. Koloskova
O. I. Filippova
A. V. Koloskov
author_sort M. N. Pautova
collection DOAJ
description Evaluation of bone marrow cytogenetic abnormalities in myelodysplastic syndrome is of great importance for confirming the clonal disease nature, determining the prognosis and choosing treatment tactics. Cytogenetic abnormalities are detected in 40–70 % of patients with myelodysplastic syndrome, and the variety of these abnormalities reflects the disease characteristics.This article describes the clinical follow-up of a patient with a myelodysplastic neoplasia with blast excess 1 and trisomy of chromosome 14.
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issn 1818-8346
2413-4023
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publishDate 2024-09-01
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series Онкогематология
spelling doaj-art-327168e796a749ba9af2c9bf4e4b27322025-08-20T03:01:03ZrusABV-pressОнкогематология1818-83462413-40232024-09-0119314915210.17650/1818-8346-2024-19-3-149-152774Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndromeM. N. Pautova0L. E. Koloskova1O. I. Filippova2A. V. Koloskov3I.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaMedical Laboratory SPbI.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaI.I. Mechnikov North-Western State Medical University, Ministry of Health of RussiaEvaluation of bone marrow cytogenetic abnormalities in myelodysplastic syndrome is of great importance for confirming the clonal disease nature, determining the prognosis and choosing treatment tactics. Cytogenetic abnormalities are detected in 40–70 % of patients with myelodysplastic syndrome, and the variety of these abnormalities reflects the disease characteristics.This article describes the clinical follow-up of a patient with a myelodysplastic neoplasia with blast excess 1 and trisomy of chromosome 14.https://oncohematology.abvpress.ru/ongm/article/view/947myelodysplastic syndromedysplasiacytogenetic abnormalitytrisomy chromosomes 14
spellingShingle M. N. Pautova
L. E. Koloskova
O. I. Filippova
A. V. Koloskov
Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
Онкогематология
myelodysplastic syndrome
dysplasia
cytogenetic abnormality
trisomy chromosomes 14
title Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
title_full Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
title_fullStr Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
title_full_unstemmed Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
title_short Trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
title_sort trisomy 14 as the only cytogenetic abnormality in myelodysplastic syndrome
topic myelodysplastic syndrome
dysplasia
cytogenetic abnormality
trisomy chromosomes 14
url https://oncohematology.abvpress.ru/ongm/article/view/947
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AT lekoloskova trisomy14astheonlycytogeneticabnormalityinmyelodysplasticsyndrome
AT oifilippova trisomy14astheonlycytogeneticabnormalityinmyelodysplasticsyndrome
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