Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer
Xanthogranulomatous cystitis is a rare, benign, chronic inflammatory disease of the bladder, mimicking malignancy with unknown etiology. Herein, we report a 57-year-old man who presented with pollakiuria, nocturia, dysuria, left flank pain, and a palpable mass on the right lower abdomen. Computerize...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2010.139 |
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| author | Sinan Ekici Isin Dogan Ekici Sevket Ruacan Ahmet Midi |
| author_facet | Sinan Ekici Isin Dogan Ekici Sevket Ruacan Ahmet Midi |
| author_sort | Sinan Ekici |
| collection | DOAJ |
| description | Xanthogranulomatous cystitis is a rare, benign, chronic inflammatory disease of the bladder, mimicking malignancy with unknown etiology. Herein, we report a 57-year-old man who presented with pollakiuria, nocturia, dysuria, left flank pain, and a palpable mass on the right lower abdomen. Computerized tomography demonstrated an obstructing 10-mm stone in the lower third of the left ureter and a 6-cm solid mass on the right at the anterolateral wall of the bladder. The mass presented local perivesical invasion at the anterolateral side. Cystouretroscopy revealed a mass protruding into the bladder cavity with edematous smooth surface. Frozen section analysis of the partial cystectomy specimen could not rule out malignancy. Therefore, radical cystoprostatectomy and ureterolithotomy were performed. Histologically, fibrosis, numerous plasma cells, eosinophils, and, immunohistochemically, CD68-positive epithelioid and foamy macrophages were detected. Localized prostatic adenocarcinoma was also found. The present case of xanthogranulomatous cystitis is the 23rd to be reported in the world literature. |
| format | Article |
| id | doaj-art-326ea303d5fb47caab9e25e91268ba2b |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-326ea303d5fb47caab9e25e91268ba2b2025-08-20T02:07:40ZengWileyThe Scientific World Journal1537-744X2010-01-01101169117310.1100/tsw.2010.139Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder CancerSinan Ekici0Isin Dogan Ekici1Sevket Ruacan2Ahmet Midi3Department of Urology, School of Medicine, Maltepe University, Istanbul, TurkeyDepartment of Urology, School of Medicine, Yeditepe University, Istanbul, TurkeyDepartment of Pathology, School of Medicine, Hacettepe University, Ankara, TurkeyDepartment of Pathology, School of Medicine, Maltepe University, Istanbul, TurkeyXanthogranulomatous cystitis is a rare, benign, chronic inflammatory disease of the bladder, mimicking malignancy with unknown etiology. Herein, we report a 57-year-old man who presented with pollakiuria, nocturia, dysuria, left flank pain, and a palpable mass on the right lower abdomen. Computerized tomography demonstrated an obstructing 10-mm stone in the lower third of the left ureter and a 6-cm solid mass on the right at the anterolateral wall of the bladder. The mass presented local perivesical invasion at the anterolateral side. Cystouretroscopy revealed a mass protruding into the bladder cavity with edematous smooth surface. Frozen section analysis of the partial cystectomy specimen could not rule out malignancy. Therefore, radical cystoprostatectomy and ureterolithotomy were performed. Histologically, fibrosis, numerous plasma cells, eosinophils, and, immunohistochemically, CD68-positive epithelioid and foamy macrophages were detected. Localized prostatic adenocarcinoma was also found. The present case of xanthogranulomatous cystitis is the 23rd to be reported in the world literature.http://dx.doi.org/10.1100/tsw.2010.139 |
| spellingShingle | Sinan Ekici Isin Dogan Ekici Sevket Ruacan Ahmet Midi Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer The Scientific World Journal |
| title | Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer |
| title_full | Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer |
| title_fullStr | Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer |
| title_full_unstemmed | Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer |
| title_short | Xanthogranulomatous Cystitis: A Challenging Imitator of Bladder Cancer |
| title_sort | xanthogranulomatous cystitis a challenging imitator of bladder cancer |
| url | http://dx.doi.org/10.1100/tsw.2010.139 |
| work_keys_str_mv | AT sinanekici xanthogranulomatouscystitisachallengingimitatorofbladdercancer AT isindoganekici xanthogranulomatouscystitisachallengingimitatorofbladdercancer AT sevketruacan xanthogranulomatouscystitisachallengingimitatorofbladdercancer AT ahmetmidi xanthogranulomatouscystitisachallengingimitatorofbladdercancer |