Importance and Relevance of Phytochemicals Present in Galenia africana

Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemi...

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Main Authors: Dario Heredia, Ivan Green, Jeremy Klaasen, Farzana Rahiman
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2022/5793436
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author Dario Heredia
Ivan Green
Jeremy Klaasen
Farzana Rahiman
author_facet Dario Heredia
Ivan Green
Jeremy Klaasen
Farzana Rahiman
author_sort Dario Heredia
collection DOAJ
description Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemicals present. Galenia africana has been used traditionally in the form of pastes, decoctions, and lotions to treat wounds and other skin-related ailments. This is a report on the phytochemical composition of G. africana and a review on the pharmacological importance and relevance of these phytochemicals. The major groups of phytochemicals identified in G. africana extracts were aliphatics, aliphatic triterpenoids, fatty acids, flavonoids, and phenolic and tocopherol compounds. These have been found to exhibit medicinal properties, thus highlighting the need to assess the safety of G. africana for topical application. The information related to the safety of the various compounds could indicate the potential risks related to accidental intake of the extract upon topical product applications. This report concludes that the quantities of the phytochemicals present in G. africana should not cause undue risk to human health, which provides comfort to pursue future work on using and developing G. africana as a therapeutic agent.
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spelling doaj-art-326c094d0d7f48aba8b79feac7e5108f2025-02-03T07:23:56ZengWileyScientifica2090-908X2022-01-01202210.1155/2022/5793436Importance and Relevance of Phytochemicals Present in Galenia africanaDario Heredia0Ivan Green1Jeremy Klaasen2Farzana Rahiman3Department of Medical BioscienceDepartment of ChemistryDepartment of Medical BioscienceDepartment of Medical BioscienceMany people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemicals present. Galenia africana has been used traditionally in the form of pastes, decoctions, and lotions to treat wounds and other skin-related ailments. This is a report on the phytochemical composition of G. africana and a review on the pharmacological importance and relevance of these phytochemicals. The major groups of phytochemicals identified in G. africana extracts were aliphatics, aliphatic triterpenoids, fatty acids, flavonoids, and phenolic and tocopherol compounds. These have been found to exhibit medicinal properties, thus highlighting the need to assess the safety of G. africana for topical application. The information related to the safety of the various compounds could indicate the potential risks related to accidental intake of the extract upon topical product applications. This report concludes that the quantities of the phytochemicals present in G. africana should not cause undue risk to human health, which provides comfort to pursue future work on using and developing G. africana as a therapeutic agent.http://dx.doi.org/10.1155/2022/5793436
spellingShingle Dario Heredia
Ivan Green
Jeremy Klaasen
Farzana Rahiman
Importance and Relevance of Phytochemicals Present in Galenia africana
Scientifica
title Importance and Relevance of Phytochemicals Present in Galenia africana
title_full Importance and Relevance of Phytochemicals Present in Galenia africana
title_fullStr Importance and Relevance of Phytochemicals Present in Galenia africana
title_full_unstemmed Importance and Relevance of Phytochemicals Present in Galenia africana
title_short Importance and Relevance of Phytochemicals Present in Galenia africana
title_sort importance and relevance of phytochemicals present in galenia africana
url http://dx.doi.org/10.1155/2022/5793436
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