The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility

The paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstru...

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Main Authors: Dipti Katre, Namrata Choudhary, Ashish Prakash Anjankar, Aakash More, Sudhanshu Dakre
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_1400_24
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author Dipti Katre
Namrata Choudhary
Ashish Prakash Anjankar
Aakash More
Sudhanshu Dakre
author_facet Dipti Katre
Namrata Choudhary
Ashish Prakash Anjankar
Aakash More
Sudhanshu Dakre
author_sort Dipti Katre
collection DOAJ
description The paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstruation. Hysterosalpingography confirmed the presence of bilateral hydrosalpinx, thus suggesting IVF as the most suitable method to conceive. The patient went through a long protocol using GnRH agonist and 14 oocytes were retrieved from her with 10 being fertilized. To avoid ovarian hyperstimulation syndrome (OHSS), all the embryos were frozen and thawed after six months of hormone replacement therapy for the preparation of the endometrium, and a single blastocyst was transferred. The patient conceived, and a subsequent β-hCG level of 256 mIU/mL proved good pregnancy status 14 days after the embryo transfer. This case demonstrates how a personalized and holistic treatment approach to the management of infertility, especially in patients with such conditions as endometriosis and hydrosalpinx, can be very fruitful.
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institution Kabale University
issn 0976-4879
0975-7406
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj-art-326551be545c41f3adbb37bd458b813c2025-01-13T10:55:26ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S4013S401610.4103/jpbs.jpbs_1400_24The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor InfertilityDipti KatreNamrata ChoudharyAshish Prakash AnjankarAakash MoreSudhanshu DakreThe paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstruation. Hysterosalpingography confirmed the presence of bilateral hydrosalpinx, thus suggesting IVF as the most suitable method to conceive. The patient went through a long protocol using GnRH agonist and 14 oocytes were retrieved from her with 10 being fertilized. To avoid ovarian hyperstimulation syndrome (OHSS), all the embryos were frozen and thawed after six months of hormone replacement therapy for the preparation of the endometrium, and a single blastocyst was transferred. The patient conceived, and a subsequent β-hCG level of 256 mIU/mL proved good pregnancy status 14 days after the embryo transfer. This case demonstrates how a personalized and holistic treatment approach to the management of infertility, especially in patients with such conditions as endometriosis and hydrosalpinx, can be very fruitful.https://journals.lww.com/10.4103/jpbs.jpbs_1400_24endometriosisgrowth hormonehydrosalpinxinfertility
spellingShingle Dipti Katre
Namrata Choudhary
Ashish Prakash Anjankar
Aakash More
Sudhanshu Dakre
The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
Journal of Pharmacy and Bioallied Sciences
endometriosis
growth hormone
hydrosalpinx
infertility
title The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
title_full The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
title_fullStr The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
title_full_unstemmed The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
title_short The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
title_sort role of gnrh agonist therapy and hysterosalpingography hsg in diagnosing and treating tubal factor infertility
topic endometriosis
growth hormone
hydrosalpinx
infertility
url https://journals.lww.com/10.4103/jpbs.jpbs_1400_24
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