The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility
The paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstru...
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Wolters Kluwer Medknow Publications
2024-12-01
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Series: | Journal of Pharmacy and Bioallied Sciences |
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Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1400_24 |
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author | Dipti Katre Namrata Choudhary Ashish Prakash Anjankar Aakash More Sudhanshu Dakre |
author_facet | Dipti Katre Namrata Choudhary Ashish Prakash Anjankar Aakash More Sudhanshu Dakre |
author_sort | Dipti Katre |
collection | DOAJ |
description | The paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstruation. Hysterosalpingography confirmed the presence of bilateral hydrosalpinx, thus suggesting IVF as the most suitable method to conceive. The patient went through a long protocol using GnRH agonist and 14 oocytes were retrieved from her with 10 being fertilized. To avoid ovarian hyperstimulation syndrome (OHSS), all the embryos were frozen and thawed after six months of hormone replacement therapy for the preparation of the endometrium, and a single blastocyst was transferred. The patient conceived, and a subsequent β-hCG level of 256 mIU/mL proved good pregnancy status 14 days after the embryo transfer. This case demonstrates how a personalized and holistic treatment approach to the management of infertility, especially in patients with such conditions as endometriosis and hydrosalpinx, can be very fruitful. |
format | Article |
id | doaj-art-326551be545c41f3adbb37bd458b813c |
institution | Kabale University |
issn | 0976-4879 0975-7406 |
language | English |
publishDate | 2024-12-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Pharmacy and Bioallied Sciences |
spelling | doaj-art-326551be545c41f3adbb37bd458b813c2025-01-13T10:55:26ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S4013S401610.4103/jpbs.jpbs_1400_24The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor InfertilityDipti KatreNamrata ChoudharyAshish Prakash AnjankarAakash MoreSudhanshu DakreThe paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstruation. Hysterosalpingography confirmed the presence of bilateral hydrosalpinx, thus suggesting IVF as the most suitable method to conceive. The patient went through a long protocol using GnRH agonist and 14 oocytes were retrieved from her with 10 being fertilized. To avoid ovarian hyperstimulation syndrome (OHSS), all the embryos were frozen and thawed after six months of hormone replacement therapy for the preparation of the endometrium, and a single blastocyst was transferred. The patient conceived, and a subsequent β-hCG level of 256 mIU/mL proved good pregnancy status 14 days after the embryo transfer. This case demonstrates how a personalized and holistic treatment approach to the management of infertility, especially in patients with such conditions as endometriosis and hydrosalpinx, can be very fruitful.https://journals.lww.com/10.4103/jpbs.jpbs_1400_24endometriosisgrowth hormonehydrosalpinxinfertility |
spellingShingle | Dipti Katre Namrata Choudhary Ashish Prakash Anjankar Aakash More Sudhanshu Dakre The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility Journal of Pharmacy and Bioallied Sciences endometriosis growth hormone hydrosalpinx infertility |
title | The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility |
title_full | The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility |
title_fullStr | The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility |
title_full_unstemmed | The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility |
title_short | The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility |
title_sort | role of gnrh agonist therapy and hysterosalpingography hsg in diagnosing and treating tubal factor infertility |
topic | endometriosis growth hormone hydrosalpinx infertility |
url | https://journals.lww.com/10.4103/jpbs.jpbs_1400_24 |
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