The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring
Osteoporosis is a common metabolic bone disease that seriously affects the quality of life and health of patients. Traditional diagnostic methods, such as dual energy X-ray absorptiometry (DXA), have limitations in early detection and dynamic monitoring, making it difficult to meet clinical needs. T...
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| Format: | Article |
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1594903/full |
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| author | Jie Fu Chi Zhang Chi Zhang |
| author_facet | Jie Fu Chi Zhang Chi Zhang |
| author_sort | Jie Fu |
| collection | DOAJ |
| description | Osteoporosis is a common metabolic bone disease that seriously affects the quality of life and health of patients. Traditional diagnostic methods, such as dual energy X-ray absorptiometry (DXA), have limitations in early detection and dynamic monitoring, making it difficult to meet clinical needs. This paper focuses on the potential of radionuclide imaging techniques, such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET), in the early diagnosis of osteoporosis. The paper further elaborates on the importance of radionuclides in evaluating the therapeutic effect of osteoporosis drugs. By summarizing current research findings, this paper aims to emphasize the core role of radionuclides in the management of osteoporosis, and provide theoretical basis and practical guidance for optimizing the diagnosis and treatment strategies of bone metabolism diseases in the future. |
| format | Article |
| id | doaj-art-3263465522ee42e697b5f4196d46d9ed |
| institution | OA Journals |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-3263465522ee42e697b5f4196d46d9ed2025-08-20T02:19:57ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-04-011610.3389/fphar.2025.15949031594903The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoringJie Fu0Chi Zhang1Chi Zhang2College of Future Technology, Peking University, Beijing, ChinaCollege of Future Technology, Peking University, Beijing, ChinaDepartment of Orthopedics, Peking University International Hospital, Beijing, ChinaOsteoporosis is a common metabolic bone disease that seriously affects the quality of life and health of patients. Traditional diagnostic methods, such as dual energy X-ray absorptiometry (DXA), have limitations in early detection and dynamic monitoring, making it difficult to meet clinical needs. This paper focuses on the potential of radionuclide imaging techniques, such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET), in the early diagnosis of osteoporosis. The paper further elaborates on the importance of radionuclides in evaluating the therapeutic effect of osteoporosis drugs. By summarizing current research findings, this paper aims to emphasize the core role of radionuclides in the management of osteoporosis, and provide theoretical basis and practical guidance for optimizing the diagnosis and treatment strategies of bone metabolism diseases in the future.https://www.frontiersin.org/articles/10.3389/fphar.2025.1594903/fullosteoporosisboneradionuclidesdiagnosisefficacy monitoring |
| spellingShingle | Jie Fu Chi Zhang Chi Zhang The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring Frontiers in Pharmacology osteoporosis bone radionuclides diagnosis efficacy monitoring |
| title | The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring |
| title_full | The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring |
| title_fullStr | The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring |
| title_full_unstemmed | The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring |
| title_short | The research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring |
| title_sort | research progress on radionuclides in osteoporosis diagnosis and drug efficacy monitoring |
| topic | osteoporosis bone radionuclides diagnosis efficacy monitoring |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2025.1594903/full |
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