Ocular Complications of Inflammatory Bowel Disease

Though inflammatory bowel disease (IBD) has a specific predilection for the intestinal tract, it is a systemic inflammatory disorder affecting multiple organs, including the eye. Ocular complications directly related to IBD are categorized as primary and secondary. Primary complications are usually...

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Main Authors: Rana Mady, Will Grover, Salim Butrus
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/438402
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author Rana Mady
Will Grover
Salim Butrus
author_facet Rana Mady
Will Grover
Salim Butrus
author_sort Rana Mady
collection DOAJ
description Though inflammatory bowel disease (IBD) has a specific predilection for the intestinal tract, it is a systemic inflammatory disorder affecting multiple organs, including the eye. Ocular complications directly related to IBD are categorized as primary and secondary. Primary complications are usually temporally associated with IBD exacerbations and tend to resolve with systemic treatment of the intestinal inflammation. These include keratopathy, episcleritis, and scleritis. Secondary complications arise from primary complications. Examples include cataract formation due to treatment with corticosteroids, scleromalacia due to scleritis, and dry eye due to hypovitaminosis A following gut resection. Some ocular manifestations of IBD can lead to significant visual morbidity and temporally associated complications can also be a herald of disease control. Furthermore, ocular manifestations of IBD can occasionally manifest before the usual intestinal manifestations, leading to an earlier diagnosis. Thus, it is important to understand the clinical presentation of possible ocular manifestations in order to initiate appropriate treatment and to help prevent significant visual morbidity.
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spelling doaj-art-325b5260dd3d48c7984db694d31b612f2025-02-03T01:23:18ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/438402438402Ocular Complications of Inflammatory Bowel DiseaseRana Mady0Will Grover1Salim Butrus2Department of Ophthalmology, Georgetown University, Washington Hospital Center, 3800 Reservoir Road NW, Washington, DC 20007, USADepartment of Ophthalmology, Georgetown University, Washington Hospital Center, 3800 Reservoir Road NW, Washington, DC 20007, USADepartment of Ophthalmology, Georgetown University and George Washington University, 900 23rd Street NW, Washington, DC 20037, USAThough inflammatory bowel disease (IBD) has a specific predilection for the intestinal tract, it is a systemic inflammatory disorder affecting multiple organs, including the eye. Ocular complications directly related to IBD are categorized as primary and secondary. Primary complications are usually temporally associated with IBD exacerbations and tend to resolve with systemic treatment of the intestinal inflammation. These include keratopathy, episcleritis, and scleritis. Secondary complications arise from primary complications. Examples include cataract formation due to treatment with corticosteroids, scleromalacia due to scleritis, and dry eye due to hypovitaminosis A following gut resection. Some ocular manifestations of IBD can lead to significant visual morbidity and temporally associated complications can also be a herald of disease control. Furthermore, ocular manifestations of IBD can occasionally manifest before the usual intestinal manifestations, leading to an earlier diagnosis. Thus, it is important to understand the clinical presentation of possible ocular manifestations in order to initiate appropriate treatment and to help prevent significant visual morbidity.http://dx.doi.org/10.1155/2015/438402
spellingShingle Rana Mady
Will Grover
Salim Butrus
Ocular Complications of Inflammatory Bowel Disease
The Scientific World Journal
title Ocular Complications of Inflammatory Bowel Disease
title_full Ocular Complications of Inflammatory Bowel Disease
title_fullStr Ocular Complications of Inflammatory Bowel Disease
title_full_unstemmed Ocular Complications of Inflammatory Bowel Disease
title_short Ocular Complications of Inflammatory Bowel Disease
title_sort ocular complications of inflammatory bowel disease
url http://dx.doi.org/10.1155/2015/438402
work_keys_str_mv AT ranamady ocularcomplicationsofinflammatoryboweldisease
AT willgrover ocularcomplicationsofinflammatoryboweldisease
AT salimbutrus ocularcomplicationsofinflammatoryboweldisease