T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions

T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions

Epstein-Barr virus (EBV)-infected B cells effectively induce T cell-mediated immune surveillance that suppresses the proliferation of EBV+ B cells and development of lymphomas. However, it remains unclear whether EBV-specific T cells are involved in the surveillance of EBV-negative general tumors. T...

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Bibliographic Details
Main Authors: Yuqi Jin, Yun Guo, Yohei Kawano, Megumi Sasatani, Shun Ohki, Keita Yamane, Yusei Ota, Yumi Tamura, Yusuke Sotomaru, Yoshihiro Baba, Tomoharu Yasuda
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
Epstein-Barr virus
LMP1
LMP2A
immune surveillance
radiation-induced tumor
T-ALL
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1597731/full
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