Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report
Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. The bacterial infection is spread via Trombiculidae mites. A 50-year-old male patient was admitted with a complaint of fever, cough, breathlessness, and irrelevant talk for five days. The patient was chronic alcoholic and hypertens...
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JCDR Research and Publications Private Limited
2025-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/20492/64201_260523_64201_CE[Ra1]_F(IS)_PF1(AG_KM)_PFA(AG_KM_IS)_PN(IS).pdf |
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| author | Maharshi Patel Sourya Acharya Samarth Shukla Shubham Nimkar Sunil Kumar |
| author_facet | Maharshi Patel Sourya Acharya Samarth Shukla Shubham Nimkar Sunil Kumar |
| author_sort | Maharshi Patel |
| collection | DOAJ |
| description | Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. The bacterial infection is spread via Trombiculidae mites. A 50-year-old male patient was admitted with a complaint of fever, cough, breathlessness, and irrelevant talk for five days. The patient was chronic alcoholic and hypertensive for one year. After investigation patient was positive for scrub typhus. The patient had hepatitis, renal failure, thrombocytopenia, and right lower lobe pneumonia. The cause of thrombocytopenia in scrub typhus individuals could be the development of Thrombotic Thrombocytopenic Purpura (TTP), Disseminated Intravascular Coagulation (DIC), and thrombotic microangiopathy. In scrub typhus patients, TTP and Multiple Organ Dysfunction Syndrome (MODS) can be avoided with early diagnosis and effective treatment. Further research is warranted in such conditions to understand the molecular mechanism as well as to prevent mortality. |
| format | Article |
| id | doaj-art-3251b7896e9542e2887503b5f80edb3d |
| institution | Kabale University |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-3251b7896e9542e2887503b5f80edb3d2025-01-18T11:51:09ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-01-011901222410.7860/JCDR/2025/64201.20492Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case ReportMaharshi Patel0Sourya Acharya1Samarth Shukla2Shubham Nimkar3Sunil Kumar4Resident, Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Professor and Head, Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Professor, Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Resident, Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Professor, Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. The bacterial infection is spread via Trombiculidae mites. A 50-year-old male patient was admitted with a complaint of fever, cough, breathlessness, and irrelevant talk for five days. The patient was chronic alcoholic and hypertensive for one year. After investigation patient was positive for scrub typhus. The patient had hepatitis, renal failure, thrombocytopenia, and right lower lobe pneumonia. The cause of thrombocytopenia in scrub typhus individuals could be the development of Thrombotic Thrombocytopenic Purpura (TTP), Disseminated Intravascular Coagulation (DIC), and thrombotic microangiopathy. In scrub typhus patients, TTP and Multiple Organ Dysfunction Syndrome (MODS) can be avoided with early diagnosis and effective treatment. Further research is warranted in such conditions to understand the molecular mechanism as well as to prevent mortality.https://jcdr.net/articles/PDF/20492/64201_260523_64201_CE[Ra1]_F(IS)_PF1(AG_KM)_PFA(AG_KM_IS)_PN(IS).pdfbacteriahepatitismitespneumoniarenal failure |
| spellingShingle | Maharshi Patel Sourya Acharya Samarth Shukla Shubham Nimkar Sunil Kumar Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report Journal of Clinical and Diagnostic Research bacteria hepatitis mites pneumonia renal failure |
| title | Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report |
| title_full | Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report |
| title_fullStr | Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report |
| title_full_unstemmed | Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report |
| title_short | Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report |
| title_sort | scrub typhus induced thrombotic thrombocytopenia a rare case report |
| topic | bacteria hepatitis mites pneumonia renal failure |
| url | https://jcdr.net/articles/PDF/20492/64201_260523_64201_CE[Ra1]_F(IS)_PF1(AG_KM)_PFA(AG_KM_IS)_PN(IS).pdf |
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