Mitochondrial Dysfunction: A New Hallmark in Hereditable Thoracic Aortic Aneurysm Development

Mitochondrial Dysfunction: A New Hallmark in Hereditable Thoracic Aortic Aneurysm Development

Thoracic aortic aneurysms (TAAs) pose a significant health burden due to their asymptomatic progression, often culminating in life-threatening aortic rupture, and due to the lack of effective pharmacological treatments. Risk factors include elevated hemodynamic stress on the ascending aorta, frequen...

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Bibliographic Details
Main Authors: Daniel Marcos-Ríos, Antonio Rochano-Ortiz, Irene San Sebastián-Jaraba, María José Fernández-Gómez, Nerea Méndez-Barbero, Jorge Oller
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
Marfan
aneurysm
mitochondria
smooth muscle cells
vascular pathology
connective tissue
Online Access:https://www.mdpi.com/2073-4409/14/8/618
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