Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Aloe-emodin ameliorates chronic kidney disease fibrosis by inhibiting PI3K-mediated signaling pathway

Chronic kidney disease (CKD) impacts a vast number of individuals worldwide, culminating in renal fibrosis. Renal fibrosis serves as the main reason for end-stage renal failure. However, the current targeted treatment methods for renal fibrosis remain scarce. Aloe-emodin (AE) is a naturally occurri...

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Bibliographic Details
Main Authors:	Ming Chen, Wenhui Zhu, Yao Chen, Jingying Shang, Wenfan Wang, Xiaoming Yan, Peng Liu, Yabin Zhou
Format:	Article
Language:	English
Published:	PAGEPress Publications 2025-08-01
Series:	European Journal of Histochemistry
Subjects:	Renal fibrosis network pharmacology PI3K/Akt/GSK3β signaling pathway
Online Access:	https://www.ejh.it/ejh/article/view/4228
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