Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Abstract Hepatic steatosis, inflammation, and fibrosis are the hallmarks of metabolic‐associated steatohepatitis (MASH), a serious health risk. This study emphasizes how important gelsolin (GSN) is to the pathophysiology of MASH. The results show that GSN is significantly overexpressed in both MASH...

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Bibliographic Details
Main Authors: Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
F‐actin
gelsolin (GSN)
metabolic‐associated steatohepatitis (MASH)
P53
YAP
Online Access:https://doi.org/10.1002/advs.202416489
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