Insulin resistance aggravates myocardial fibrosis in non-diabetic hypertensive patients by altering the function of epicardial adipose tissue: a cardiac magnetic resonance study

Insulin resistance aggravates myocardial fibrosis in non-diabetic hypertensive patients by altering the function of epicardial adipose tissue: a cardiac magnetic resonance study

Abstract Background The effect of insulin resistance (IR) on epicardial adipose tissue (EAT) remains uncertain. This study aimed to investigate how early-stage IR influences EAT, contributing to myocardial fibrosis and left ventricular dysfunction in non-diabetic patients with hypertension. Methods...

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Bibliographic Details
Main Authors:	Runze Zhu, Wenxian Wang, Yan Gao, Jian Wang, Bowen Li, Zhenyu Cheng, Congshan Ji, Hui Gu, Xianshun Yuan, Shifeng Yang, Ximing Wang
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Series:	Diabetology & Metabolic Syndrome
Subjects:	Epicardial adipose tissue Hypertensive Triglyceride-glucose index Insulin resistance Myocardial fibrosis
Online Access:	https://doi.org/10.1186/s13098-025-01695-8
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