Surgery impairs glymphatic activity and cognitive function in aged mice
Abstract Delirium is a common complication in elderly surgical patients and is associated with an increased risk of dementia. Although advanced age is a major risk factor, the mechanisms underlying postoperative delirium remain poorly understood. The glymphatic system, a brain-wide network of periva...
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Main Authors: | Kai Chen, Xingyu Du, Melissa A. Chao, Zhongcong Xie, Guang Yang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13041-025-01177-y |
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