Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients
The etiologies of secondary idiopathic thrombocytopenic purpura (ITP) include infection, autoimmune disease, and immunodeficiency. We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. The platelet count of an 81-year-old woman fell to 27,000/μL afte...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2016/7913092 |
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| author | Joji Nagasaki Masahiro Manabe Kentaro Ido Hiroyoshi Ichihara Yasutaka Aoyama Tadanobu Ohta Yoshio Furukawa Atsuko Mugitani |
| author_facet | Joji Nagasaki Masahiro Manabe Kentaro Ido Hiroyoshi Ichihara Yasutaka Aoyama Tadanobu Ohta Yoshio Furukawa Atsuko Mugitani |
| author_sort | Joji Nagasaki |
| collection | DOAJ |
| description | The etiologies of secondary idiopathic thrombocytopenic purpura (ITP) include infection, autoimmune disease, and immunodeficiency. We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. The platelet count of an 81-year-old woman fell to 27,000/μL after she received an influenza vaccination. A 75-year-old woman developed thrombocytopenia (5,000 platelets/μL) after receiving an influenza vaccination. An 87-year-old woman whose laboratory test values included a platelet count of 2,000/μL experienced genital bleeding after receiving an influenza vaccination. After Helicobacter pylori (HP) eradication or corticosteroid treatment, all of the patients’ platelet counts increased. Influenza vaccination is an underlying etiology of ITP in elderly patients. HP eradication or corticosteroid treatment is effective for these patients. Clinicians should be aware of the association between ITP and influenza vaccinations. |
| format | Article |
| id | doaj-art-323a70604c474077981016a866671e26 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-323a70604c474077981016a866671e262025-02-03T01:07:50ZengWileyCase Reports in Hematology2090-65602090-65792016-01-01201610.1155/2016/79130927913092Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly PatientsJoji Nagasaki0Masahiro Manabe1Kentaro Ido2Hiroyoshi Ichihara3Yasutaka Aoyama4Tadanobu Ohta5Yoshio Furukawa6Atsuko Mugitani7Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanDepartment of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, JapanThe etiologies of secondary idiopathic thrombocytopenic purpura (ITP) include infection, autoimmune disease, and immunodeficiency. We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. The platelet count of an 81-year-old woman fell to 27,000/μL after she received an influenza vaccination. A 75-year-old woman developed thrombocytopenia (5,000 platelets/μL) after receiving an influenza vaccination. An 87-year-old woman whose laboratory test values included a platelet count of 2,000/μL experienced genital bleeding after receiving an influenza vaccination. After Helicobacter pylori (HP) eradication or corticosteroid treatment, all of the patients’ platelet counts increased. Influenza vaccination is an underlying etiology of ITP in elderly patients. HP eradication or corticosteroid treatment is effective for these patients. Clinicians should be aware of the association between ITP and influenza vaccinations.http://dx.doi.org/10.1155/2016/7913092 |
| spellingShingle | Joji Nagasaki Masahiro Manabe Kentaro Ido Hiroyoshi Ichihara Yasutaka Aoyama Tadanobu Ohta Yoshio Furukawa Atsuko Mugitani Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients Case Reports in Hematology |
| title | Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients |
| title_full | Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients |
| title_fullStr | Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients |
| title_full_unstemmed | Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients |
| title_short | Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients |
| title_sort | postinfluenza vaccination idiopathic thrombocytopenic purpura in three elderly patients |
| url | http://dx.doi.org/10.1155/2016/7913092 |
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