High Frequency Oscillatory Ventilation

High frequency oscillatory (HFO) ventilation using low tidal volume and peak airway pressures is extremely efficient at eliminating carbon dioxide and raising pH in the newborn infant with acute respiratory failure. Improvement in oxygenation requires a strategy of sustained or repetitive inflations...

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Main Authors: AC Bryan, D Bohn
Format: Article
Language:English
Published: Wiley 1996-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1996/306724
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author AC Bryan
D Bohn
author_facet AC Bryan
D Bohn
author_sort AC Bryan
collection DOAJ
description High frequency oscillatory (HFO) ventilation using low tidal volume and peak airway pressures is extremely efficient at eliminating carbon dioxide and raising pH in the newborn infant with acute respiratory failure. Improvement in oxygenation requires a strategy of sustained or repetitive inflations to 25 to 30 cm H2O in order to place the lung on the deflation limb of the pressure-volume curve. This strategy has also been shown to decrease the amount of secondary lung injury in animal models. Experience of the use of HFO ventilation as a rescue therapy as well as several published controlled trials have shown improved outcomes and a decrease in the use of extracorporeal membrane oxygenation when it has been used in newborns.
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series Canadian Respiratory Journal
spelling doaj-art-323405d78d474056accb488f1a05580b2025-02-03T05:52:36ZengWileyCanadian Respiratory Journal1198-22411996-01-013636836910.1155/1996/306724High Frequency Oscillatory VentilationAC BryanD BohnHigh frequency oscillatory (HFO) ventilation using low tidal volume and peak airway pressures is extremely efficient at eliminating carbon dioxide and raising pH in the newborn infant with acute respiratory failure. Improvement in oxygenation requires a strategy of sustained or repetitive inflations to 25 to 30 cm H2O in order to place the lung on the deflation limb of the pressure-volume curve. This strategy has also been shown to decrease the amount of secondary lung injury in animal models. Experience of the use of HFO ventilation as a rescue therapy as well as several published controlled trials have shown improved outcomes and a decrease in the use of extracorporeal membrane oxygenation when it has been used in newborns.http://dx.doi.org/10.1155/1996/306724
spellingShingle AC Bryan
D Bohn
High Frequency Oscillatory Ventilation
Canadian Respiratory Journal
title High Frequency Oscillatory Ventilation
title_full High Frequency Oscillatory Ventilation
title_fullStr High Frequency Oscillatory Ventilation
title_full_unstemmed High Frequency Oscillatory Ventilation
title_short High Frequency Oscillatory Ventilation
title_sort high frequency oscillatory ventilation
url http://dx.doi.org/10.1155/1996/306724
work_keys_str_mv AT acbryan highfrequencyoscillatoryventilation
AT dbohn highfrequencyoscillatoryventilation