Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review
Introduction and Objective. Every year, 20 million people are diagnosed with cancer, most of whom undergo chemotherapy at some stage of treatment. Chemotherapy is associated with various side effects, with hair loss being one of the most visible and socially stigmatizing. This study aimed to evalua...
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Kazimierz Wielki University
2025-01-01
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| Series: | Journal of Education, Health and Sport |
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| Online Access: | https://apcz.umk.pl/JEHS/article/view/56966 |
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| author | Izabela Ochonska Karolina Jaglarz Maciej Kuca Marcin Cholewa Maria Jasiewicz |
| author_facet | Izabela Ochonska Karolina Jaglarz Maciej Kuca Marcin Cholewa Maria Jasiewicz |
| author_sort | Izabela Ochonska |
| collection | DOAJ |
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Introduction and Objective. Every year, 20 million people are diagnosed with cancer, most of whom undergo chemotherapy at some stage of treatment. Chemotherapy is associated with various side effects, with hair loss being one of the most visible and socially stigmatizing. This study aimed to evaluate and summarize existing strategies for preventing chemotherapy-induced hair loss.
Review methods. Data for this paper were gathered using electronic databases like PubMed and Google Scholar, with a focus on papers from the last five years, particularly clinical trials, double-blind randomized studies, meta-analyses, and reviews.
State of Knowledge. Around 65% of chemotherapy patients experience hair loss. Currently, the FDA has approved one method for preventing chemotherapy-induced alopecia (CIA): scalp cooling. This technique induces localized vasoconstriction, reducing the penetration of chemotherapy drugs into hair follicles. Scalp cooling is generally well-tolerated. Other potential methods include scalp injections of autologous platelet-rich plasma, which contains growth factors and anti-inflammatory cytokines, and microneedling, an invasive procedure with uncertain effectiveness, especially as a standalone treatment, that aims to stimulate angiogenesis.
Conclusions. Effective, reliable methods for preventing chemotherapy-induced alopecia (CIA) are still lacking. A holistic approach to oncology care is needed to address the diverse needs of patients. Discovering new preventive methods would greatly improve patients' ability to cope with cancer treatment. However, most current approaches show only moderate efficacy or are still in clinical trials.
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| format | Article |
| id | doaj-art-3231e7a591a5447f986653132dd38b44 |
| institution | Kabale University |
| issn | 2391-8306 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-3231e7a591a5447f986653132dd38b442025-01-09T08:16:41ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-01-017710.12775/JEHS.2025.77.56966Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature reviewIzabela Ochonska0https://orcid.org/0009-0007-4645-5771Karolina Jaglarz1https://orcid.org/0009-0009-7316-4042Maciej Kuca2https://orcid.org/0000-0002-6749-7360Marcin Cholewa3https://orcid.org/0009-0002-8520-8187Maria Jasiewicz4https://orcid.org/0009-0008-0718-2528Medical University of Silesia, ul. Poniatowskiego 15, 40-055 KatowiceKatowice Oncology Center, ul. Raciborska 26, 40-074 KatowiceKatowice Oncology Center, ul. Raciborska 26, 40-074 KatowiceProvincial Hospital of St. Luke in Tarnów, ul. Lwowska 178a, 33-100 TarnówMedical Center in Łańcut Ltd., ul. Paderewskiego 5, 37-100 Łańcut Introduction and Objective. Every year, 20 million people are diagnosed with cancer, most of whom undergo chemotherapy at some stage of treatment. Chemotherapy is associated with various side effects, with hair loss being one of the most visible and socially stigmatizing. This study aimed to evaluate and summarize existing strategies for preventing chemotherapy-induced hair loss. Review methods. Data for this paper were gathered using electronic databases like PubMed and Google Scholar, with a focus on papers from the last five years, particularly clinical trials, double-blind randomized studies, meta-analyses, and reviews. State of Knowledge. Around 65% of chemotherapy patients experience hair loss. Currently, the FDA has approved one method for preventing chemotherapy-induced alopecia (CIA): scalp cooling. This technique induces localized vasoconstriction, reducing the penetration of chemotherapy drugs into hair follicles. Scalp cooling is generally well-tolerated. Other potential methods include scalp injections of autologous platelet-rich plasma, which contains growth factors and anti-inflammatory cytokines, and microneedling, an invasive procedure with uncertain effectiveness, especially as a standalone treatment, that aims to stimulate angiogenesis. Conclusions. Effective, reliable methods for preventing chemotherapy-induced alopecia (CIA) are still lacking. A holistic approach to oncology care is needed to address the diverse needs of patients. Discovering new preventive methods would greatly improve patients' ability to cope with cancer treatment. However, most current approaches show only moderate efficacy or are still in clinical trials. https://apcz.umk.pl/JEHS/article/view/56966chemotherapy-induced alopeciaCIAhair losscancerhair loss treatmentchemotherapy |
| spellingShingle | Izabela Ochonska Karolina Jaglarz Maciej Kuca Marcin Cholewa Maria Jasiewicz Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review Journal of Education, Health and Sport chemotherapy-induced alopecia CIA hair loss cancer hair loss treatment chemotherapy |
| title | Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review |
| title_full | Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review |
| title_fullStr | Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review |
| title_full_unstemmed | Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review |
| title_short | Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review |
| title_sort | non pharmacological therapies in the treatment of chemotherapy induced alopecia a literature review |
| topic | chemotherapy-induced alopecia CIA hair loss cancer hair loss treatment chemotherapy |
| url | https://apcz.umk.pl/JEHS/article/view/56966 |
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